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NCT01665937 · ClinicalTrials.gov registry record · Phase 1

STA-9090 in Patients With Advanced Hepatocellular Cancer

A Phase 1 study of Hepatocellular Carcinoma, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target
3
Study locations

NCT01665937 is a Phase 1 study of Hepatocellular Carcinoma that has completed, run by Massachusetts General Hospital. The registered enrollment target is 16 participants, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 1 state.

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The verdict

NCT01665937, a Phase 1 study of Hepatocellular Carcinoma, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target
3
Study locations

Study Summary

STA-9090 works by inhibiting the function of a protein in tumor cells called Hsp90. Hsp90 is thought to play a role in tumor growth. By interfering with this protein's function, STA-9090 may help kill tumor cells. This drug has been used in other research studies and information from those studies suggests that this agent may help to slow tumor growth in HCC. The purpose of this research study is to find the highest dose of STA-9090 that can safely be given to participants with advanced HCC. The investigators will also get more information about the safety of STA-9090 and perform tests to learn more about how STA-9090 affects the body.

Conditions Studied

Interventions

  • DRUG STA-9090

Study Locations (3)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston
  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2010-08
Est. Completion 2014-03
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT01665937

The ClinicalTrials.gov registry entry for NCT01665937 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (94% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which STA-9090 is the first listed.

NCT01665937 reports 3 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01665937 about?

NCT01665937 is a clinical study titled "STA-9090 in Patients With Advanced Hepatocellular Cancer". STA-9090 works by inhibiting the function of a protein in tumor cells called Hsp90. Hsp90 is thought to play a role in tumor growth. By interfering with this protein's function, STA-9090 may help kill tumor cells. This drug has been used in other research studies and information from those studies s...

What is the current status of trial NCT01665937?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2010-08. Estimated completion is 2014-03.

What conditions does trial NCT01665937 study?

This clinical trial studies the following conditions: Hepatocellular Carcinoma.

What interventions are being tested in trial NCT01665937?

The interventions under investigation include: STA-9090 (DRUG).

Who is sponsoring clinical trial NCT01665937?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01665937 being conducted?

This trial has 3 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.