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NCT01538407 · ClinicalTrials.gov registry record · NA
Strengthening Exercise and Quadriceps Force During Walking
A NA study of Knee Osteoarthritis, sponsored by Frederiksberg University Hospital.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 2
- Study locations
NCT01538407: Completed NA study of Knee Osteoarthritis, sponsored by Frederiksberg University Hospital.
NCT01538407 is a NA study of Knee Osteoarthritis that has completed, run by Frederiksberg University Hospital. The registered enrollment target is 30 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01538407, a NA study of Knee Osteoarthritis, has completed, sponsored by Frederiksberg University Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a longitudinal, randomized, controlled interventional multi centric study on the effects of lower leg strengthening exercise on quadriceps force during walking in people with knee osteoarthritis. At each study centre twenty subjects will be included, for a total of 40 participants. Subjects will be randomized equally (1:1) into 1 active arm and 1 control arm. The objective of the study is to evaluate the effect of twelve weeks of quadriceps strengthening on the mechanical output of the quadriceps during locomotion. A secondary purpose is to explore the relationship between quadriceps strengthening and compressive knee loadings. The hypothesis is that quadriceps strength training will not change quadriceps force, power, and work in locomotion in people with knee osteoarthritis. Primary outcome is quadriceps force during walking, secondary outputs are quadriceps power and work and knee compressive loads during walking. Explorative measures are isometric and concentric isokinetic leg muscle strength, radiographic score of the knee (Kellgren and Lawrence), a one-leg rise from chair test (maximum number of reps) and a lateral step-up test (maximum number of reps).
Primary Outcome
Estimates of the quadriceps muscle forces during locomotion are calculated using a biomechanical model based on data from gait analysis
Conditions Studied
Interventions
- OTHER Strength Training
Study Locations (2)
North Carolina
- The College of Health and Human Performance, Department of Exercise and Sport Science, Minges Coliseum - Greenville
Other
- The Parker Institute, Frederiksberg University Hospital - Copenhagen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2012-03 |
| Est. Completion | 2013-10 |
| Phase | NA |
What the finished NCT01538407 record still lists
NCT01538407 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which Strength Training is the first listed.
NCT01538407 reports a single indexed study location in North Carolina, Other.
Frequently Asked Questions
What is clinical trial NCT01538407 about?
NCT01538407 is a clinical study titled "Strengthening Exercise and Quadriceps Force During Walking". This is a longitudinal, randomized, controlled interventional multi centric study on the effects of lower leg strengthening exercise on quadriceps force during walking in people with knee osteoarthritis. At each study centre twenty subjects will be included, for a total of 40 participants. Subjects ...
What is the current status of trial NCT01538407?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2012-03. Estimated completion is 2013-10.
What conditions does trial NCT01538407 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT01538407?
The interventions under investigation include: Strength Training (OTHER).
Who is sponsoring clinical trial NCT01538407?
This trial is sponsored by Frederiksberg University Hospital, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01538407 being conducted?
This trial has 2 study locations across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01538407's enrollment target sits among peer trials
30 80th of 101 higher than 15 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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