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NCT01500980 · ClinicalTrials.gov registry record · Phase 1
Malaria Challenge in Healthy Volunteers
A Phase 1 study, sponsored by Seattle Children's Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT01500980: Completed Phase 1 study, sponsored by Seattle Children's Hospital.
NCT01500980 is a Phase 1 study that has completed, run by Seattle Children's Hospital. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01500980, a Phase 1 study, has completed, sponsored by Seattle Children's Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if sterile, protective immunity to malaria can be induced by malaria parasite exposure limited to the early liver stage of the parasite lifecycle.
Primary Outcome
Detection for evidence of patent parasitemia and time to parasitemia following challenge with homologous P. falciparum sporozoites in subjects with confirmed exposure to P. falciparum sporozoites and early liver stage parasites only
Interventions
- DRUG Chloroquine
- DRUG Primaquine
- BIOLOGICAL P. falciparum infection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2011-12 |
| Est. Completion | 2012-11 |
| Phase | Phase 1 |
What the finished NCT01500980 record still lists
NCT01500980 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 3 interventions - of which Chloroquine is the first listed.
NCT01500980 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01500980 about?
NCT01500980 is a clinical study titled "Malaria Challenge in Healthy Volunteers". The purpose of this study is to determine if sterile, protective immunity to malaria can be induced by malaria parasite exposure limited to the early liver stage of the parasite lifecycle.
What is the current status of trial NCT01500980?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2011-12. Estimated completion is 2012-11.
What interventions are being tested in trial NCT01500980?
The interventions under investigation include: Chloroquine (DRUG), Primaquine (DRUG), P. falciparum infection (BIOLOGICAL).
Who is sponsoring clinical trial NCT01500980?
This trial is sponsored by Seattle Children's Hospital, which has 168 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01500980's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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