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NCT01156155 · ClinicalTrials.gov registry record
Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis
A clinical trial of Rheumatoid Arthritis and Osteoarthritis, sponsored by University of Nebraska.
- Completed
- Registry status
- 617
- Enrollment target
- 1
- Study location
NCT01156155: Completed study of Rheumatoid Arthritis and Osteoarthritis, sponsored by University of Nebraska.
NCT01156155 is a study of Rheumatoid Arthritis and Osteoarthritis that has completed, run by University of Nebraska. The registered enrollment target is 617 participants, below the 4,687-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01156155, a study of Rheumatoid Arthritis and Osteoarthritis, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- 617 participants
- Enrollment target
- 1
- Study location
Study Summary
Periodontitis (PD) has been postulated to be a risk factor for the onset and progression of rheumatoid arthritis (RA). Recent reports suggest that infection with Porphyromonas gingivalis (P. gingivalis), a major oral pathogen in PD, could play a pivotal role in the development RA. The objective of this study is to examine the relationship of PD and P. gingivalis infection with the risk and severity of RA.
Primary Outcome
Clinically defined PD will be more common in RA patients than in controls. 1.B.: Clinically defined PD will be associated with greater RA disease severity including autoantibody status and the presence and extent of radiographic disease progression. 1.C.: The associations of clinically defined PD with RA risk and severity will be explained by the presence of antibody to P. gingivalis.
Conditions Studied
Interventions
- PROCEDURE Blood draw
- OTHER questionnaires
- RADIATION Digital xray of jaw and teeth
- PROCEDURE Periodontal Examination
- OTHER Bilateral digital xray of hands
Study Locations (1)
Nebraska
- Veterans Affairs Medical Center, Omaha - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 617 participants |
| Start Date | 2010-07-14 |
| Est. Completion | 2018-08-30 |
What the finished NCT01156155 record still lists
NCT01156155 is an observational study that tracks outcomes without assigning an intervention. The registered 617 participants enrollment target is mid-sized for trials with a published cap, below the 4,687-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (87% lower).
The record links to 3 conditions, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 5 interventions - of which Blood draw is the first listed.
NCT01156155 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT01156155 about?
NCT01156155 is a clinical study titled "Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis". Periodontitis (PD) has been postulated to be a risk factor for the onset and progression of rheumatoid arthritis (RA). Recent reports suggest that infection with Porphyromonas gingivalis (P. gingivalis), a major oral pathogen in PD, could play a pivotal role in the development RA. The objective of t...
What is the current status of trial NCT01156155?
This trial is currently completed. The enrollment target is 617 participants. The study started on 2010-07-14. Estimated completion is 2018-08-30.
What conditions does trial NCT01156155 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis, Osteoarthritis, Periodontal Disease.
What interventions are being tested in trial NCT01156155?
The interventions under investigation include: Blood draw (PROCEDURE), questionnaires (OTHER), Digital xray of jaw and teeth (RADIATION), Periodontal Examination (PROCEDURE), Bilateral digital xray of hands (OTHER).
Who is sponsoring clinical trial NCT01156155?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01156155 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01156155's enrollment target sits among peer trials
617 35th of 197 higher than 163 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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