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NCT01089114 · ClinicalTrials.gov registry record
Cardiovascular Radiologic and Metabolic Assessment in HIV: An Investigation of Pathophysiology
A clinical trial of HIV and Cardiovascular Disease, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- 168
- Enrollment target
- 1
- Study location
NCT01089114 is a study of HIV and Cardiovascular Disease that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 168 participants, below the 439-participant average among 303 other HIV trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01089114, a study of HIV and Cardiovascular Disease, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- 168 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Antiretroviral therapy has increased the lifespan of people with human immunodeficiency virus (HIV), but recent research suggests that people with HIV also have an increased risk of developing cardiovascular disease. To better understand the prevalence and effects of heart disease in people with HIV, researchers are interested in comparing heart imaging and metabolism studies to see if there are differences between HIV-positive and HIV-negative people. Objectives: \- To study metabolism and heart function in people with HIV compared with healthy HIV-negative volunteers. Eligibility: \- Individuals at least 18 years of age who either have been diagnosed with HIV or are healthy HIV-negative volunteers. Design: * Participants will be evaluated with a physical exam, detailed medical history, and routine blood and urine tests including HIV testing. * Participants will have the following imaging scans: * Cardiac magnetic resonance imaging (MRI) to study the health of the heart and blood vessels * Magnetic resonance spectroscopy (MRS) of the heart, liver, and skeletal muscle * Cardiac computerized tomography (CT) scan to measure calcium levels in the heart and nearby arteries * Dual-energy x-ray absorptiometry (DEXA) scan to measure body fat and muscle mass. * Stable isotope infusion to evaluate how the body processes fat (which will require an overnight stay before the test) * Participants will also have blood tests, an echocardiogram, and an electrocardiogram to evaluate heart function.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2010-03-08 |
| Est. Completion | 2015-08-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01089114
The ClinicalTrials.gov registry entry for NCT01089114 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 439-participant average among 303 other HIV trials with a reported enrollment target (62% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 0 interventions.
NCT01089114 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT01089114 about?
NCT01089114 is a clinical study titled "Cardiovascular Radiologic and Metabolic Assessment in HIV: An Investigation of Pathophysiology". Background: \- Antiretroviral therapy has increased the lifespan of people with human immunodeficiency virus (HIV), but recent research suggests that people with HIV also have an increased risk of developing cardiovascular disease. To better understand the prevalence and effects of heart disease in...
What is the current status of trial NCT01089114?
This trial is currently completed. The enrollment target is 168 participants. The study started on 2010-03-08. Estimated completion is 2015-08-07.
What conditions does trial NCT01089114 study?
This clinical trial studies the following conditions: HIV, Cardiovascular Disease.
Who is sponsoring clinical trial NCT01089114?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01089114 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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