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NCT01084733 · ClinicalTrials.gov registry record
Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer
A clinical trial of Oropharyngeal Cancer and Oral Cavity Cancer, sponsored by Mahesh Kudrimoti.
- Completed
- Registry status
- 115
- Enrollment target
- 1
- Study location
NCT01084733: Completed study of Oropharyngeal Cancer and Oral Cavity Cancer, sponsored by Mahesh Kudrimoti.
NCT01084733 is a study of Oropharyngeal Cancer and Oral Cavity Cancer that has completed, run by Mahesh Kudrimoti. The registered enrollment target is 115 participants, below the 185-participant average among 25 other Oropharyngeal Cancer trials with a reported enrollment target (38% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01084733, a study of Oropharyngeal Cancer and Oral Cavity Cancer, has completed, sponsored by Mahesh Kudrimoti.
- COMPLETED
- Registry status
- 115 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to evaluate the relationship between serum nicotine levels and tumor response of squamous cell cancers of the head and neck (SCCHN) to radiotherapy alone or in combination with chemotherapy. Correlation of RECIST response, volumatic response, pathologic response (in patients receiving post-treatment neck dissection), and hemodynamic response (tumor oxygenation and blood flow) will be performed.
Primary Outcome
RECIST criteria will be used as a correlate for standardization of tumor response. Volumetric analysis may provide better assessment of bulky tumor size that may have a large necrotic or hypoxic component that may be resistant to treatment. Furthermore, volumetric analysis has been associated with a higher rate of concordance to response based upon RECIST criteria.
Conditions Studied
Study Locations (1)
Kentucky
- Markey Cancer Center - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 115 participants |
| Start Date | 2007-08 |
| Est. Completion | 2019-06-30 |
What the finished NCT01084733 record still lists
NCT01084733 is an observational study that tracks outcomes without assigning an intervention. The registered 115 participants enrollment target is mid-sized for trials with a published cap, below the 185-participant average among 25 other Oropharyngeal Cancer trials with a reported enrollment target (38% lower).
The record links to 5 conditions, with Oropharyngeal Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT01084733 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT01084733 about?
NCT01084733 is a clinical study titled "Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer". The objective of this study is to evaluate the relationship between serum nicotine levels and tumor response of squamous cell cancers of the head and neck (SCCHN) to radiotherapy alone or in combination with chemotherapy. Correlation of RECIST response, volumatic response, pathologic response (in p...
What is the current status of trial NCT01084733?
This trial is currently completed. The enrollment target is 115 participants. The study started on 2007-08. Estimated completion is 2019-06-30.
What conditions does trial NCT01084733 study?
This clinical trial studies the following conditions: Oropharyngeal Cancer, Oral Cavity Cancer, Larynx Cancer, Lip Cancer, Pharyngeal Cancer.
Who is sponsoring clinical trial NCT01084733?
This trial is sponsored by Mahesh Kudrimoti, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01084733 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Oropharyngeal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01084733's enrollment target sits among peer trials
115 10th of 25 higher than 16 of 25 other Oropharyngeal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Oropharyngeal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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