Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05862792 · ClinicalTrials.gov registry record

Liposomal Bupivacaine and Transoral Robotic Surgery

A clinical trial of Postoperative Pain and Oropharyngeal Cancer, sponsored by Geisinger Clinic.

Recruiting
Registry status
80
Enrollment target
1
Study location

NCT05862792: Recruiting study of Postoperative Pain and Oropharyngeal Cancer, sponsored by Geisinger Clinic.

NCT05862792 is a study of Postoperative Pain and Oropharyngeal Cancer that is actively recruiting participants, run by Geisinger Clinic. The registered enrollment target is 80 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05862792, a study of Postoperative Pain and Oropharyngeal Cancer, is actively recruiting participants, sponsored by Geisinger Clinic.

RECRUITING
Registry status
80 participants
Enrollment target
1
Study location

Study Summary

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.

Primary Outcome

We will be measuring subjects' postoperative maximum visual analog pain scores on each postoperative day. Scale: 0-10, 0 represents no pain and 10 represents the worst pain

Interventions

  • DRUG Liposomal bupivacaine

Study Locations (1)

Pennsylvania

  • Geisinger Medical Center - Danville

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2023-06-01
Est. Completion 2026-01-15
Geisinger Clinic

107 total trials

What NCT05862792 shows while recruiting

NCT05862792 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (65% lower).

The record links to 4 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 1 intervention - of which Liposomal bupivacaine is the first listed.

NCT05862792 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05862792 about?

NCT05862792 is a clinical study titled "Liposomal Bupivacaine and Transoral Robotic Surgery". This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Lipo...

What is the current status of trial NCT05862792?

This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2023-06-01. Estimated completion is 2026-01-15.

What conditions does trial NCT05862792 study?

This clinical trial studies the following conditions: Postoperative Pain, Oropharyngeal Cancer, Dysphagia, Oropharyngeal, Transoral Robotic Surgery.

What interventions are being tested in trial NCT05862792?

The interventions under investigation include: Liposomal bupivacaine (DRUG).

Who is sponsoring clinical trial NCT05862792?

This trial is sponsored by Geisinger Clinic, which has 107 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05862792 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Postoperative Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05862792's enrollment target sits among peer trials

80 69th of 120 higher than 47 of 120 other Postoperative Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01243931 · 80 participants · NA

    Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

  • NCT01659203 · 80 participants · Phase 1

    Proton or Photon RT for Retroperitoneal Sarcomas

  • NCT01803451 · 80 participants · Early Phase 1

    Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

  • NCT01964859 · 80 participants · Phase 2

    Feasibility Study for Fibroblast Autologous Skin Grafts

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05862792, the US trial registry maintained by the National Library of Medicine. NCT05862792 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.