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NCT01049841 · ClinicalTrials.gov registry record · Phase 1

Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors

A Phase 1 study of Pediatric Solid Tumors, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target
1
Study location

NCT01049841 is a Phase 1 study of Pediatric Solid Tumors that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 23 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01049841, a Phase 1 study of Pediatric Solid Tumors, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to test the safety and effectiveness of 2 drugs, perifosine in combination with temsirolimus in children with solid tumors. Neither drug is currently part of the standard treatment of solid tumors in children. Both drugs have been tested alone to treat solid tumors in children with little success. There is now new insight that if given together, perifosine and temsirolimus may work together to stop the growth of solid tumors and may also make them shrink. The doctor wants to find out what effects; good and/or bad, perifosine in combination with temsirolimus has on the patient and the cancer. The doctors are testing four different dose schedules of perifosine with temsirolimus and the patient will be asked to partake in one of the dose schedules. The dose schedule will be lower for those enrolled early in the study.

Conditions Studied

Interventions

  • DRUG perifosine + temsirolimus

Study Locations (1)

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2010-01
Est. Completion 2017-03
Phase Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT01049841

The ClinicalTrials.gov registry entry for NCT01049841 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pediatric Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which perifosine + temsirolimus is the first listed.

NCT01049841 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01049841 about?

NCT01049841 is a clinical study titled "Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors". The purpose of this study is to test the safety and effectiveness of 2 drugs, perifosine in combination with temsirolimus in children with solid tumors. Neither drug is currently part of the standard treatment of solid tumors in children. Both drugs have been tested alone to treat solid tumors in ch...

What is the current status of trial NCT01049841?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2010-01. Estimated completion is 2017-03.

What conditions does trial NCT01049841 study?

This clinical trial studies the following conditions: Pediatric Solid Tumors.

What interventions are being tested in trial NCT01049841?

The interventions under investigation include: perifosine + temsirolimus (DRUG).

Who is sponsoring clinical trial NCT01049841?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01049841 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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