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NCT01049841 · ClinicalTrials.gov registry record · Phase 1
Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors
A Phase 1 study of Pediatric Solid Tumors, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT01049841: Completed Phase 1 study of Pediatric Solid Tumors, sponsored by Memorial Sloan Kettering Cancer Center.
NCT01049841 is a Phase 1 study of Pediatric Solid Tumors that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01049841, a Phase 1 study of Pediatric Solid Tumors, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test the safety and effectiveness of 2 drugs, perifosine in combination with temsirolimus in children with solid tumors. Neither drug is currently part of the standard treatment of solid tumors in children. Both drugs have been tested alone to treat solid tumors in children with little success. There is now new insight that if given together, perifosine and temsirolimus may work together to stop the growth of solid tumors and may also make them shrink. The doctor wants to find out what effects; good and/or bad, perifosine in combination with temsirolimus has on the patient and the cancer. The doctors are testing four different dose schedules of perifosine with temsirolimus and the patient will be asked to partake in one of the dose schedules. The dose schedule will be lower for those enrolled early in the study.
Conditions Studied
Interventions
- DRUG perifosine + temsirolimus
Study Locations (1)
New York
- Memorial Sloan-Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2010-01 |
| Est. Completion | 2017-03 |
| Phase | Phase 1 |
What the finished NCT01049841 record still lists
NCT01049841 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Pediatric Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which perifosine + temsirolimus is the first listed.
NCT01049841 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01049841 about?
NCT01049841 is a clinical study titled "Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors". The purpose of this study is to test the safety and effectiveness of 2 drugs, perifosine in combination with temsirolimus in children with solid tumors. Neither drug is currently part of the standard treatment of solid tumors in children. Both drugs have been tested alone to treat solid tumors in ch...
What is the current status of trial NCT01049841?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2010-01. Estimated completion is 2017-03.
What conditions does trial NCT01049841 study?
This clinical trial studies the following conditions: Pediatric Solid Tumors.
What interventions are being tested in trial NCT01049841?
The interventions under investigation include: perifosine + temsirolimus (DRUG).
Who is sponsoring clinical trial NCT01049841?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01049841 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01049841's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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