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NCT00950001 · ClinicalTrials.gov registry record · Phase 3
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases
A Phase 3 study of Metastatic Malignant Neoplasm in the Brain, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 3
- Development phase
- 132
- Enrollment target
- 1
- Study location
NCT00950001: Active Phase 3 study of Metastatic Malignant Neoplasm in the Brain, sponsored by M.D. Anderson Cancer Center.
NCT00950001 is a Phase 3 study of Metastatic Malignant Neoplasm in the Brain that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 132 participants, above the 85-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (55% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00950001, a Phase 3 study of Metastatic Malignant Neoplasm in the Brain, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 132 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized phase III trial studies stereotactic radiosurgery to see how well it works compared to clinical observation after surgery in treating patients with brain metastases. Stereotactic radiosurgery, a type of radiation therapy, may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
Primary Outcome
A univariate test between groups will be conducted using a log rank test of Kaplan-Meier survival estimates and multivariate analyses will be conducted via the Cox proportional hazards model. The hazard ratio comparing each arm will be computed for each endpoint with and without adjustment for other covariates. Confidence intervals (95%) will be computed for the hazard ratio estimates. The proportion of patients experiencing neurological complications will be computed via univariate and multivar
Conditions Studied
Interventions
- RADIATION Stereotactic Radiosurgery
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2009-08-13 |
| Est. Completion | 2027-04-30 |
| Phase | Phase 3 |
What the registry record for NCT00950001 still lists
NCT00950001 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, above the 85-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (55% higher).
The record links to 1 condition, with Metastatic Malignant Neoplasm in the Brain appearing as the primary indexed condition, and to 1 intervention - of which Stereotactic Radiosurgery is the first listed.
NCT00950001 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00950001 about?
NCT00950001 is a clinical study titled "Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases". This randomized phase III trial studies stereotactic radiosurgery to see how well it works compared to clinical observation after surgery in treating patients with brain metastases. Stereotactic radiosurgery, a type of radiation therapy, may be able to send x-rays directly to the tumor and cause les...
What is the current status of trial NCT00950001?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 132 participants. The study started on 2009-08-13. Estimated completion is 2027-04-30.
What conditions does trial NCT00950001 study?
This clinical trial studies the following conditions: Metastatic Malignant Neoplasm in the Brain.
What interventions are being tested in trial NCT00950001?
The interventions under investigation include: Stereotactic Radiosurgery (RADIATION).
Who is sponsoring clinical trial NCT00950001?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00950001 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metastatic Malignant Neoplasm in the Brain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00950001's enrollment target sits among peer trials
132 11th of 43 higher than 33 of 43 other Metastatic Malignant Neoplasm in the Brain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Malignant Neoplasm in the Brain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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