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NCT00887146 · ClinicalTrials.gov registry record · Phase 3
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
A Phase 3 study of Brain and Central Nervous System Tumors, sponsored by Alliance for Clinical Trials in Oncology.
- Active
- Registry status
- Phase 3
- Development phase
- 305
- Enrollment target
- 20
- Study locations
NCT00887146 is a Phase 3 study of Brain and Central Nervous System Tumors that is active but no longer recruiting, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 305 participants, above the 177-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (72% higher). The trial reports 20 study locations across 4 states.
The verdict
NCT00887146, a Phase 3 study of Brain and Central Nervous System Tumors, is active but no longer recruiting, sponsored by Alliance for Clinical Trials in Oncology.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 305 participants
- Enrollment target
- 20
- Study locations
Study Summary
Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant temozolomide versus radiation with adjuvant PCV is more effective in treating anaplastic glioma or low grade glioma.
Conditions Studied
Interventions
- RADIATION radiotherapy
- DRUG concomitant temozolomide (TMZ)
- DRUG procarbazine
- DRUG adjuvant temozolomide (TMZ)
- DRUG CCNU
Study Locations (20)
California
- Kaiser Permanente-Anaheim - Anaheim
- Sutter Cancer Centers Radiation Oncology Services-Auburn - Auburn
- Mills-Peninsula Medical Center - Burlingame
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park - Cameron Park
- Community Cancer Institute - Clovis
- University Oncology Associates - Clovis
- UC San Diego Moores Cancer Center - La Jolla
- Kaiser Permanente Los Angeles Medical Center - Los Angeles
- Cedars Sinai Medical Center - Los Angeles
Alaska
- Anchorage Associates in Radiation Medicine - Anchorage
- Alaska Oncology and Hematology LLC - Anchorage
- Alaska Women's Cancer Care - Anchorage
- Anchorage Oncology Centre - Anchorage
- Katmai Oncology Group - Anchorage
- Providence Alaska Medical Center - Anchorage
Arizona
- Saint Joseph's Hospital and Medical Center - Phoenix
- Arizona Oncology-Deer Valley Center - Phoenix
- Arizona Oncology Services Foundation - Scottsdale
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
- Providence Hospital - Mobile
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 305 participants |
| Start Date | 2009-09 |
| Est. Completion | 2029-10-31 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00887146
The ClinicalTrials.gov registry entry for NCT00887146 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 305 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 177-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (72% higher). The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 5 interventions - of which radiotherapy is the first listed.
NCT00887146 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Alaska, Arizona.
Frequently Asked Questions
What is clinical trial NCT00887146 about?
NCT00887146 is a clinical study titled "Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma". Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and ...
What is the current status of trial NCT00887146?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 305 participants. The study started on 2009-09. Estimated completion is 2029-10-31.
What conditions does trial NCT00887146 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.
What interventions are being tested in trial NCT00887146?
The interventions under investigation include: radiotherapy (RADIATION), concomitant temozolomide (TMZ) (DRUG), procarbazine (DRUG), adjuvant temozolomide (TMZ) (DRUG), CCNU (DRUG).
Who is sponsoring clinical trial NCT00887146?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00887146 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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