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NCT00861328 · ClinicalTrials.gov registry record · Phase 1

Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin

A Phase 1 study of Advanced Solid Tumors, sponsored by Traws Pharma.

Completed
Registry status
Phase 1
Development phase
18
Enrollment target
1
Study location

NCT00861328 is a Phase 1 study of Advanced Solid Tumors that has completed, run by Traws Pharma. The registered enrollment target is 18 participants, below the 199-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00861328, a Phase 1 study of Advanced Solid Tumors, has completed, sponsored by Traws Pharma.

COMPLETED
Registry status
Phase 1
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

Treatment of cancer is often improved if two or more drugs are used in combination. In animal studies, the use of the combination of ON 01910.Na (a new, unapproved drug) and irinotecan or oxaliplatin (two approved and extensively used anti-cancer drugs) gave better results against tumor cells than the use of any of the single drugs alone. In addition, the use of the combinations did not result in an increase of side effects. This clinical trial will determine what is the highest dose of ON 01910.Na that can be given safely in combination with either irinotecan or oxaliplatin in human patients.

Conditions Studied

Interventions

  • DRUG ON 01910.Na and irinotecan
  • DRUG ON 01910.Na and oxaliplatin

Study Locations (1)

New York

  • Albert Einstein Cancer Center - The Bronx

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2008-02
Est. Completion 2011-07
Phase Phase 1

Sponsor

Traws Pharma

25 total trials

What the Registry Record Tells You About NCT00861328

The ClinicalTrials.gov registry entry for NCT00861328 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 199-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (91% lower). The listed sponsor is Traws Pharma, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which ON 01910.Na and irinotecan is the first listed.

NCT00861328 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00861328 about?

NCT00861328 is a clinical study titled "Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin". Treatment of cancer is often improved if two or more drugs are used in combination. In animal studies, the use of the combination of ON 01910.Na (a new, unapproved drug) and irinotecan or oxaliplatin (two approved and extensively used anti-cancer drugs) gave better results against tumor cells than t...

What is the current status of trial NCT00861328?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2008-02. Estimated completion is 2011-07.

What conditions does trial NCT00861328 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT00861328?

The interventions under investigation include: ON 01910.Na and irinotecan (DRUG), ON 01910.Na and oxaliplatin (DRUG).

Who is sponsoring clinical trial NCT00861328?

This trial is sponsored by Traws Pharma, which has 25 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00861328 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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