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NCT00856050 · ClinicalTrials.gov registry record · Phase 2
Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma
A Phase 2 study of Leiomyosarcoma, sponsored by Dana-Farber Cancer Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
- 1
- Study location
NCT00856050: Completed Phase 2 study of Leiomyosarcoma, sponsored by Dana-Farber Cancer Institute.
NCT00856050 is a Phase 2 study of Leiomyosarcoma that has completed, run by Dana-Farber Cancer Institute. The registered enrollment target is 27 participants, below the 120-participant average among 16 other Leiomyosarcoma trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00856050, a Phase 2 study of Leiomyosarcoma, has completed, sponsored by Dana-Farber Cancer Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to determine if letrozole is effective at controlling the growth or spread of estrogen and/or progesterone receptor positive uterine leiomyosarcoma. This drug has been used in research studies for other cancers and is currently approved by the FDA for use in breast cancer. Because letrozole lowers hormone levels in the body, it may be helpful to control tumors that express hormone receptors ( ER/PR).
Primary Outcome
Data below are reported as progression free rate (%).
Conditions Studied
Interventions
- DRUG letrozole
Study Locations (1)
Massachusetts
- Dana-Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2009-02 |
| Est. Completion | 2014-03 |
| Phase | Phase 2 |
What the finished NCT00856050 record still lists
NCT00856050 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 120-participant average among 16 other Leiomyosarcoma trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Leiomyosarcoma appearing as the primary indexed condition, and to 1 intervention - of which letrozole is the first listed.
NCT00856050 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00856050 about?
NCT00856050 is a clinical study titled "Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma". The purpose of this research study is to determine if letrozole is effective at controlling the growth or spread of estrogen and/or progesterone receptor positive uterine leiomyosarcoma. This drug has been used in research studies for other cancers and is currently approved by the FDA for use in bre...
What is the current status of trial NCT00856050?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2009-02. Estimated completion is 2014-03.
What conditions does trial NCT00856050 study?
This clinical trial studies the following conditions: Leiomyosarcoma.
What interventions are being tested in trial NCT00856050?
The interventions under investigation include: letrozole (DRUG).
Who is sponsoring clinical trial NCT00856050?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00856050 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Leiomyosarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00856050's enrollment target sits among peer trials
27 12th of 16 higher than 5 of 16 other Leiomyosarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Leiomyosarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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