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NCT00828984 · ClinicalTrials.gov registry record · Phase 2
Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer
A Phase 2 study of Colorectal Carcinoma and Adenomatous Polyp, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 87
- Enrollment target
- 3
- Study locations
NCT00828984: Completed Phase 2 study of Colorectal Carcinoma and Adenomatous Polyp, sponsored by National Cancer Institute (NCI).
NCT00828984 is a Phase 2 study of Colorectal Carcinoma and Adenomatous Polyp that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 87 participants, below the 1,095-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (92% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00828984, a Phase 2 study of Colorectal Carcinoma and Adenomatous Polyp, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 87 participants
- Enrollment target
- 3
- Study locations
Study Summary
This randomized phase II trial studies how well macrogol 3350-based oral osmotic laxative (polyethylene glycol 3350) works in preventing cancer in patients at risk of colorectal cancer. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of macrogol 3350-based oral osmotic laxative may stop cancer from growing in patients who are at risk of colorectal cancer.
Primary Outcome
Evaluate the effect of polyethylene glycol (PEG) 3350 (administered at 8g or 17g/day for six months) versus placebo on EGFR expression.
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Laboratory Biomarker Analysis
- DRUG macrogol 3350-based oral osmotic laxative
Study Locations (3)
Illinois
- University of Chicago - Chicago
- NorthShore University HealthSystem-Evanston Hospital - Evanston
Massachusetts
- Boston Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2009-10 |
| Est. Completion | 2014-10 |
| Phase | Phase 2 |
What the finished NCT00828984 record still lists
NCT00828984 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 1,095-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Colorectal Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT00828984 reports a single indexed study location in Illinois, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00828984 about?
NCT00828984 is a clinical study titled "Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer". This randomized phase II trial studies how well macrogol 3350-based oral osmotic laxative (polyethylene glycol 3350) works in preventing cancer in patients at risk of colorectal cancer. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of macrogol 3350-based oral osmot...
What is the current status of trial NCT00828984?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 87 participants. The study started on 2009-10. Estimated completion is 2014-10.
What conditions does trial NCT00828984 study?
This clinical trial studies the following conditions: Colorectal Carcinoma, Adenomatous Polyp.
What interventions are being tested in trial NCT00828984?
The interventions under investigation include: Placebo (OTHER), Laboratory Biomarker Analysis (OTHER), macrogol 3350-based oral osmotic laxative (DRUG).
Who is sponsoring clinical trial NCT00828984?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00828984 being conducted?
This trial has 3 study locations across Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00828984's enrollment target sits among peer trials
87 33rd of 53 higher than 21 of 53 other Colorectal Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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