Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00745290 · ClinicalTrials.gov registry record · Phase 3

A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Undergoing Total Knee Arthroplasty

A Phase 3 study of Postoperative Pain, sponsored by Pacira Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
245
Enrollment target
19
Study locations

NCT00745290 is a Phase 3 study of Postoperative Pain that has completed, run by Pacira Pharmaceuticals. The registered enrollment target is 245 participants, roughly in line with the 228-participant average among 63 other Postoperative Pain trials with a reported enrollment target. The trial reports 19 study locations across 11 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00745290, a Phase 3 study of Postoperative Pain, has completed, sponsored by Pacira Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
245 participants
Enrollment target
19
Study locations

Study Summary

The primary objective is to demonstrate that SKY0402 is superior when compared to bupivacaine HCl in the management of postoperative pain for patients undergoing total knee arthroplasty.

Conditions Studied

Interventions

  • DRUG Bupivacaine HCl
  • DRUG SKY0402

Study Locations (19)

California

  • Scripps - La Jolla
  • Accurate Clinical Trials, Inc. - Laguna Hills
  • Physicans Clinical Research Corp. - Laguna Hills
  • Cedars of Sinai Medical Center - Los Angeles

Alabama

  • West Alabama Research, Inc. - Birmingham
  • Horizon Research Group, Inc., Alabama Orthopaedic Clinic - Mobile
  • Drug Research and Analysis Corporation - Montgomery

North Carolina

  • CTMG, Inc. - Greenville
  • Duke University Medical Center - Raleigh-Durham

Pennsylvania

  • Allegheny Pain Management - Altoona
  • Ilumina Clinical Associates - Johnstown

Texas

  • Texas Orthopedic Specialists, PA - Grapevine
  • Memorial Hermann City Hospital - Houston

Arizona

  • Sun Health Research Institute, Core Institute - Sun City West

Georgia

  • Atlanta Knee and Sports Medicine - Decatur

Illinois

  • Rush University Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 245 participants
Start Date 2008-08
Est. Completion 2009-02
Phase Phase 3

Sponsor

Pacira Pharmaceuticals

88 total trials

What the Registry Record Tells You About NCT00745290

The ClinicalTrials.gov registry entry for NCT00745290 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 245 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 228-participant average among 63 other Postoperative Pain trials with a reported enrollment target. The listed sponsor is Pacira Pharmaceuticals, which has 88 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Bupivacaine HCl is the first listed.

NCT00745290 reports 19 study locations spanning 11 distinct geographic areas - top geographies include California, Alabama, North Carolina.

Frequently Asked Questions

What is clinical trial NCT00745290 about?

NCT00745290 is a clinical study titled "A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Undergoing Total Knee Arthroplasty". The primary objective is to demonstrate that SKY0402 is superior when compared to bupivacaine HCl in the management of postoperative pain for patients undergoing total knee arthroplasty.

What is the current status of trial NCT00745290?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 245 participants. The study started on 2008-08. Estimated completion is 2009-02.

What conditions does trial NCT00745290 study?

This clinical trial studies the following conditions: Postoperative Pain.

What interventions are being tested in trial NCT00745290?

The interventions under investigation include: Bupivacaine HCl (DRUG), SKY0402 (DRUG).

Who is sponsoring clinical trial NCT00745290?

This trial is sponsored by Pacira Pharmaceuticals, which has 88 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00745290 being conducted?

This trial has 19 study locations across Alabama, Arizona, California, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Postoperative Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.