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NCT00683774 · ClinicalTrials.gov registry record · NA
Insulin and Polycystic Ovary Syndrome
A NA study of PCOS, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT00683774: Completed NA study of PCOS, sponsored by Virginia Commonwealth University.
NCT00683774 is a NA study of PCOS that has completed, run by Virginia Commonwealth University. The registered enrollment target is 21 participants, below the 81-participant average among 8 other PCOS trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00683774, a NA study of PCOS, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
Increased insulin levels leads to increased secretion of D-chiro inositol(DCI) from the kidneys in women with PCOS, but not in normal women. This leads to a reduction in circulating DCI and insulin stimulated release of DCI-IPG.To determine if decreasing circulating insulin directly by inhibition of islet insulin release with diazoxide in obese women with PCOS 1)decreases the renal clearance of DCI and 2) increases the circulating concentration of DCI.
Primary Outcome
Following inhibition of insulin release using diazoxide, measured renal clearance of D-chiro inositol (DCI) via urinary Chiro-inositol dci assay
Conditions Studied
Interventions
- DRUG diazoxide
Study Locations (1)
Virginia
- General Clinical Research Center - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2005-11 |
| Est. Completion | 2008-12 |
| Phase | NA |
What the finished NCT00683774 record still lists
NCT00683774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 81-participant average among 8 other PCOS trials with a reported enrollment target (74% lower).
The record links to 1 condition, with PCOS appearing as the primary indexed condition, and to 1 intervention - of which diazoxide is the first listed.
NCT00683774 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT00683774 about?
NCT00683774 is a clinical study titled "Insulin and Polycystic Ovary Syndrome". Increased insulin levels leads to increased secretion of D-chiro inositol(DCI) from the kidneys in women with PCOS, but not in normal women. This leads to a reduction in circulating DCI and insulin stimulated release of DCI-IPG.To determine if decreasing circulating insulin directly by inhibition of...
What is the current status of trial NCT00683774?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2005-11. Estimated completion is 2008-12.
What conditions does trial NCT00683774 study?
This clinical trial studies the following conditions: PCOS.
What interventions are being tested in trial NCT00683774?
The interventions under investigation include: diazoxide (DRUG).
Who is sponsoring clinical trial NCT00683774?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00683774 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00683774's enrollment target sits among peer trials
21 8th of 8 higher than 1 of 8 other PCOS trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PCOS trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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