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Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease
NCT00660673 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to provide continued access to levodopa-carbidopa intestinal gel (LCIG), to participants who have already participated in an open-label efficacy and safety study with the same treatment (Study S187.3.003 \[NCT00360568\] or Study S187.3.004 \[NCT00335153\]).
Conditions Studied
Interventions
- DRUG Levodopa-Carbidopa Intestinal Gel (LCIG)
- DEVICE CADD-Legacy® 1400 ambulatory infusion pump
- DEVICE Percutaneous Endoscopic Gastrostomy with jejunal extension tube (PEG-J)
Study Locations (20)
Florida
- Bradenton Research Center, Inc /ID# 49929 — Bradenton
- Neurologic Consultants, PA /ID# 49918 — Fort Lauderdale
- University of Florida - Archer /ID# 49935 — Gainesville
- University of Florida /ID# 49922 — Jacksonville
- Charlotte Neurological Service /ID# 49916 — Port Charlotte
- University of South Florida /ID# 49919 — Tampa
California
- The Research Center of Southern California /ID# 49928 — Encinitas
- The Parkinson's & Movement Disorder Institute - Fountain Valley /ID# 49915 — Fountain Valley
- Universtiy of Southern California /ID# 49913 — Los Angeles
Illinois
- Northwestern University Feinberg School of Medicine /ID# 49944 — Chicago
- Rush University Medical Center /ID# 49930 — Chicago
Maryland
- Univ Maryland School Medicine /ID# 49934 — Baltimore
- Johns Hopkins University /ID# 49937 — Baltimore
Alabama
- University of Alabama at Birmingham /ID# 49941 — Birmingham
Colorado
- Colorado Neurological Institute /ID# 49927 — Englewood
District of Columbia
- Georgetown University Hospital /ID# 49931 — Washington D.C.
Georgia
- Georgia Regents University /ID# 49938 — Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 262 participants |
| Start Date | 2009-11-13 |
| Est. Completion | 2021-11-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00660673
The ClinicalTrials.gov registry entry for NCT00660673 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 262 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 603 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Advanced Parkinson's Disease appearing as the primary indexed condition, and to 3 interventions — of which Levodopa-Carbidopa Intestinal Gel (LCIG) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00660673 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00660673 about?
NCT00660673 is a clinical study titled "Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease". The primary objective of this study is to provide continued access to levodopa-carbidopa intestinal gel (LCIG), to participants who have already participated in an open-label efficacy and safety study with the same treatment (Study S187.3.003 \[NCT00360568\] or Study S187.3.004 \[NCT00335153\]).
What is the current status of trial NCT00660673?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 262 participants. The study started on 2009-11-13. Estimated completion is 2021-11-30.
What conditions does trial NCT00660673 study?
This clinical trial studies the following conditions: Advanced Parkinson's Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00660673?
The interventions under investigation include: Levodopa-Carbidopa Intestinal Gel (LCIG) (DRUG), CADD-Legacy® 1400 ambulatory infusion pump (DEVICE), Percutaneous Endoscopic Gastrostomy with jejunal extension tube (PEG-J) (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00660673?
This trial is sponsored by AbbVie, which has 603 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00660673 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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