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NCT07422675 · ClinicalTrials.gov registry record · Phase 1

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

A Phase 1 study of PARKINSON DISEASE (Disorder) and Advanced Parkinson's Disease, sponsored by Serina Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
4
Study locations

NCT07422675 is a Phase 1 study of PARKINSON DISEASE (Disorder) and Advanced Parkinson's Disease that is actively recruiting participants, run by Serina Therapeutics. The registered enrollment target is 40 participants, roughly in line with the 37-participant average among 5 other PARKINSON DISEASE (Disorder) trials with a reported enrollment target. The trial reports 4 study locations across 4 states.

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The verdict

NCT07422675, a Phase 1 study of PARKINSON DISEASE (Disorder) and Advanced Parkinson's Disease, is actively recruiting participants, sponsored by Serina Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
4
Study locations

Study Summary

This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.

Conditions Studied

PARKINSON DISEASE (Disorder) Advanced Parkinson's Disease

Interventions

  • DRUG SER-252 (PEOZ-apomorphine)
  • DEVICE enFuse

Study Locations (4)

Florida

  • Quest Research Institute - Lake Mary

North Carolina

  • Velocity Clinical Research - Durham

South Australia

  • CMAX - Adelaide

Victoria

  • Monash - Melbourne

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-02-01
Est. Completion 2027-01-31
Phase Phase 1

Sponsor

Serina Therapeutics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07422675

The ClinicalTrials.gov registry entry for NCT07422675 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 37-participant average among 5 other PARKINSON DISEASE (Disorder) trials with a reported enrollment target. The listed sponsor is Serina Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with PARKINSON DISEASE (Disorder) appearing as the primary indexed condition, and to 2 interventions - of which SER-252 (PEOZ-apomorphine) is the first listed.

NCT07422675 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Florida, North Carolina, South Australia.

Frequently Asked Questions

What is clinical trial NCT07422675 about?

NCT07422675 is a clinical study titled "SAD Study in Patients With Parkinson's Disease and Motor Fluctuations". This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.

What is the current status of trial NCT07422675?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2026-02-01. Estimated completion is 2027-01-31.

What conditions does trial NCT07422675 study?

This clinical trial studies the following conditions: PARKINSON DISEASE (Disorder), Advanced Parkinson's Disease.

What interventions are being tested in trial NCT07422675?

The interventions under investigation include: SER-252 (PEOZ-apomorphine) (DRUG), enFuse (DEVICE).

Who is sponsoring clinical trial NCT07422675?

This trial is sponsored by Serina Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07422675 being conducted?

This trial has 4 study locations across Florida, North Carolina, South Australia, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.