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NCT00638027 · ClinicalTrials.gov registry record · Phase 4

Memantine for Spasticity in MS Patients

A Phase 4 study of Multiple Sclerosis, sponsored by University of Rochester.

Completed
Registry status
Phase 4
Development phase
21
Enrollment target
1
Study location

NCT00638027 is a Phase 4 study of Multiple Sclerosis that has completed, run by University of Rochester. The registered enrollment target is 21 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00638027, a Phase 4 study of Multiple Sclerosis, has completed, sponsored by University of Rochester.

COMPLETED
Registry status
Phase 4
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

Participants (n=20) will be identified at routine care visits performed at the Rochester Multiple Sclerosis Center. Eligible participants will have MS by McDonald Criteria,7 and will have a modified Ashworth spasticity rating8 of two or higher in at least one lower extremity muscle group. Participants will be seen at screening, one, and three months, and will be evaluated using the modified Ashworth scale,8 pendulum test,9 toe tapping test,10 manual muscle testing,11 timed 25 foot walk,12 and Multiple Sclerosis Functional Composite.13 The type and severity of any adverse events will be recorded using standard definitions. Participants will be instructed to call between visits to inform the investigators regarding any adverse events they experience. Follow-up will continue until all adverse events resolve or stabilize.

Conditions Studied

Interventions

  • DRUG placebo
  • DRUG memantine

Study Locations (1)

New York

  • University of Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2006-07
Est. Completion 2009-02
Phase Phase 4

Sponsor

University of Rochester

636 total trials

What the Registry Record Tells You About NCT00638027

The ClinicalTrials.gov registry entry for NCT00638027 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower). The listed sponsor is University of Rochester, which has 636 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT00638027 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00638027 about?

NCT00638027 is a clinical study titled "Memantine for Spasticity in MS Patients". Participants (n=20) will be identified at routine care visits performed at the Rochester Multiple Sclerosis Center. Eligible participants will have MS by McDonald Criteria,7 and will have a modified Ashworth spasticity rating8 of two or higher in at least one lower extremity muscle group. Participan...

What is the current status of trial NCT00638027?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 21 participants. The study started on 2006-07. Estimated completion is 2009-02.

What conditions does trial NCT00638027 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT00638027?

The interventions under investigation include: placebo (DRUG), memantine (DRUG).

Who is sponsoring clinical trial NCT00638027?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00638027 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.