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NCT00630721 · ClinicalTrials.gov registry record · NA
Characterization of Interferon Beta -1b-Induced Tolerizing Effect in Dendritic Cells
A NA study of Multiple Sclerosis, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT00630721: Completed NA study of Multiple Sclerosis, sponsored by University of North Carolina, Chapel Hill.
NCT00630721 is a NA study of Multiple Sclerosis that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 56 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00630721, a NA study of Multiple Sclerosis, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
Determine the in-vivo mechanism of action of INF-B-1b as it's mechanisms of action are not completely understood. We propose that high dose exogenous recombinant IFN-B-1b induces tolerizing effect on DC-dependent T-cell differentiation in patients with MS by inducing the expression of SOCS3 in DCs.
Conditions Studied
Interventions
- OTHER IFNbeta-1b
Study Locations (1)
North Carolina
- University of North Carolina - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2007-09 |
| Est. Completion | 2011-03-15 |
| Phase | NA |
What the finished NCT00630721 record still lists
NCT00630721 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which IFNbeta-1b is the first listed.
NCT00630721 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00630721 about?
NCT00630721 is a clinical study titled "Characterization of Interferon Beta -1b-Induced Tolerizing Effect in Dendritic Cells". Determine the in-vivo mechanism of action of INF-B-1b as it's mechanisms of action are not completely understood. We propose that high dose exogenous recombinant IFN-B-1b induces tolerizing effect on DC-dependent T-cell differentiation in patients with MS by inducing the expression of SOCS3 in DCs.
What is the current status of trial NCT00630721?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2007-09. Estimated completion is 2011-03-15.
What conditions does trial NCT00630721 study?
This clinical trial studies the following conditions: Multiple Sclerosis.
What interventions are being tested in trial NCT00630721?
The interventions under investigation include: IFNbeta-1b (OTHER).
Who is sponsoring clinical trial NCT00630721?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00630721 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00630721's enrollment target sits among peer trials
56 172nd of 315 higher than 144 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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