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NCT00540761 · ClinicalTrials.gov registry record · NA

Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique

A NA study of Coronary Arteriosclerosis, sponsored by Massachusetts General Hospital.

Active
Registry status
NA
Development phase
320
Enrollment target
3
Study locations

NCT00540761: Active NA study of Coronary Arteriosclerosis, sponsored by Massachusetts General Hospital.

NCT00540761 is a NA study of Coronary Arteriosclerosis that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 320 participants, below the 689-participant average among 11 other Coronary Arteriosclerosis trials with a reported enrollment target (54% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00540761, a NA study of Coronary Arteriosclerosis, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
320 participants
Enrollment target
3
Study locations

Study Summary

Atherosclerosis, a condition in which fatty deposits of plaque build up along the inner walls of arteries, is a condition that may increase the risk of having a heart attack. Previous studies have shown that the presence of a specific kind of plaque, known as vulnerable plaque, is often found in people who have had a heart attack. This study will use a new imaging technique called optical frequency domain imaging (OFDI) to examine the presence of vulnerable plaques in people with coronary artery disease.

Primary Outcome

Number of subjects with vulnerable plaques

Conditions Studied

Interventions

  • DEVICE OFDI imaging

Study Locations (3)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Lahey Clinic - Burlington

New York

  • Columbia Presbyterian Medical Center - New York

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2007-07-25
Est. Completion 2028-12
Phase NA
Massachusetts General Hospital

2,032 total trials

What the registry record for NCT00540761 still lists

NCT00540761 is an interventional study that assigns participants to a tested intervention. The registered 320 participants enrollment target is mid-sized for trials with a published cap, below the 689-participant average among 11 other Coronary Arteriosclerosis trials with a reported enrollment target (54% lower).

The record links to 1 condition, with Coronary Arteriosclerosis appearing as the primary indexed condition, and to 1 intervention - of which OFDI imaging is the first listed.

NCT00540761 reports a single indexed study location in Massachusetts, New York.

Frequently Asked Questions

What is clinical trial NCT00540761 about?

NCT00540761 is a clinical study titled "Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique". Atherosclerosis, a condition in which fatty deposits of plaque build up along the inner walls of arteries, is a condition that may increase the risk of having a heart attack. Previous studies have shown that the presence of a specific kind of plaque, known as vulnerable plaque, is often found in peo...

What is the current status of trial NCT00540761?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 320 participants. The study started on 2007-07-25. Estimated completion is 2028-12.

What conditions does trial NCT00540761 study?

This clinical trial studies the following conditions: Coronary Arteriosclerosis.

What interventions are being tested in trial NCT00540761?

The interventions under investigation include: OFDI imaging (DEVICE).

Who is sponsoring clinical trial NCT00540761?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00540761 being conducted?

This trial has 3 study locations across Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Arteriosclerosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00540761's enrollment target sits among peer trials

320 7th of 11 higher than 5 of 11 other Coronary Arteriosclerosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Arteriosclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00540761, the US trial registry maintained by the National Library of Medicine. NCT00540761 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.