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NCT00267774 · ClinicalTrials.gov registry record · NA

Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)

A NA study of Coronary Arteriosclerosis, sponsored by Stanford University.

Completed
Registry status
NA
Development phase
1,005
Enrollment target
2
Study locations

NCT00267774 is a NA study of Coronary Arteriosclerosis that has completed, run by Stanford University. The registered enrollment target is 1,005 participants, above the 626-participant average among 11 other Coronary Arteriosclerosis trials with a reported enrollment target (61% higher). The trial reports 2 study locations across 2 states.

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The verdict

NCT00267774, a NA study of Coronary Arteriosclerosis, has completed, sponsored by Stanford University.

COMPLETED
Registry status
NA
Development phase
1,005 participants
Enrollment target
2
Study locations

Study Summary

In this multicenter, international study we are evaluating two approaches to determine which coronary artery narrowings require stent placement in patients with multivessel coronary artery disease. Patients will be randomized to an angiographic strategy, where only coronary angiography is used to determine which lesions to stent or to a pressure wire strategy where fractional flow reserve, an index measured with the pressure wire, will be used to determine which lesions to stent. The primary outcome will be major adverse cardiac events at 1 year. A secondary outcome will be cost-effectiveness.

Conditions Studied

Interventions

  • DEVICE Fractional flow reserve
  • PROCEDURE Angio-guided PCI

Study Locations (2)

California

  • Stanford University School of Medicine - Stanford

Other

  • Catharina Hospital - Eindhoven

Trial Details

FieldValue
Enrollment Target 1,005 participants
Start Date 2006-01
Est. Completion 2015-09
Phase NA

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT00267774

The ClinicalTrials.gov registry entry for NCT00267774 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 1,005 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 626-participant average among 11 other Coronary Arteriosclerosis trials with a reported enrollment target (61% higher). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Coronary Arteriosclerosis appearing as the primary indexed condition, and to 2 interventions - of which Fractional flow reserve is the first listed.

NCT00267774 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Other.

Frequently Asked Questions

What is clinical trial NCT00267774 about?

NCT00267774 is a clinical study titled "Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)". In this multicenter, international study we are evaluating two approaches to determine which coronary artery narrowings require stent placement in patients with multivessel coronary artery disease. Patients will be randomized to an angiographic strategy, where only coronary angiography is used to de...

What is the current status of trial NCT00267774?

This trial is currently completed. It is a NA study. The enrollment target is 1,005 participants. The study started on 2006-01. Estimated completion is 2015-09.

What conditions does trial NCT00267774 study?

This clinical trial studies the following conditions: Coronary Arteriosclerosis.

What interventions are being tested in trial NCT00267774?

The interventions under investigation include: Fractional flow reserve (DEVICE), Angio-guided PCI (PROCEDURE).

Who is sponsoring clinical trial NCT00267774?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00267774 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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