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NCT00431756 · ClinicalTrials.gov registry record
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
A clinical trial of Gastroesophageal Reflux and Barrett Esophagus, sponsored by Johns Hopkins University.
- Active
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT00431756: Active study of Gastroesophageal Reflux and Barrett Esophagus, sponsored by Johns Hopkins University.
NCT00431756 is a study of Gastroesophageal Reflux and Barrett Esophagus that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 600 participants, below the 2,868-participant average among 33 other Gastroesophageal Reflux trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00431756, a study of Gastroesophageal Reflux and Barrett Esophagus, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can warn of a progression to esophageal cancer.
Primary Outcome
To see if changes in certain areas of DNA can predict risk for esophageal cancer
Conditions Studied
Study Locations (1)
Maryland
- Johns Hopkins Hospital - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2002-05-01 |
| Est. Completion | 2026-06-01 |
What the registry record for NCT00431756 still lists
NCT00431756 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 2,868-participant average among 33 other Gastroesophageal Reflux trials with a reported enrollment target (79% lower).
The record links to 3 conditions, with Gastroesophageal Reflux appearing as the primary indexed condition, and to 0 interventions.
NCT00431756 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00431756 about?
NCT00431756 is a clinical study titled "Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus". The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can warn of a progression to esophageal cancer.
What is the current status of trial NCT00431756?
This trial is currently active not recruiting. The enrollment target is 600 participants. The study started on 2002-05-01. Estimated completion is 2026-06-01.
What conditions does trial NCT00431756 study?
This clinical trial studies the following conditions: Gastroesophageal Reflux, Barrett Esophagus, Esophageal Neoplasm.
Who is sponsoring clinical trial NCT00431756?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00431756 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00431756's enrollment target sits among peer trials
600 3rd of 33 higher than 31 of 33 other Gastroesophageal Reflux trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gastroesophageal Reflux trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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