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NCT00340509 · ClinicalTrials.gov registry record

A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study

A clinical trial of Genetics, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

Completed
Registry status
1,888
Enrollment target
1
Study location

NCT00340509 is a study of Genetics that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 1,888 participants, above the 943-participant average among 4 other Genetics trials with a reported enrollment target (100% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00340509, a study of Genetics, has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

COMPLETED
Registry status
1,888 participants
Enrollment target
1
Study location

Study Summary

Studies have shown that there is a significant association between serum bilirubin concentrations and risk of coronary artery disease (CAD). So far, no linkage analysis in humans between serum bilirubin and DNA markers has been reported. The purpose of this protocol is to identify chromosome regions that contain quantitative trait loci (QTL) involved in serum bilirubin metabolism and bilirubin concentration. In the Framingham Study, a 10cM genome scan (about 400 markers) has been conducted in more than three hundred families. Serum bilirubin was measured in the first and second exams of the Framingham Offspring. These data provide us the opportunity to undertake linkage analyses to map QTL of serum bilirubin.

Conditions Studied

Study Locations (1)

Maryland

  • National Heart, Lung and Blood Institute (NHLBI), 9000 Rockville Pike - Bethesda

Trial Details

FieldValue
Enrollment Target 1,888 participants
Start Date 2001-10-26
Est. Completion 2013-07-23

What the Registry Record Tells You About NCT00340509

The ClinicalTrials.gov registry entry for NCT00340509 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 1,888 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 943-participant average among 4 other Genetics trials with a reported enrollment target (100% higher). The listed sponsor is National Heart, Lung, and Blood Institute (NHLBI), which has 501 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Genetics appearing as the primary indexed condition, and to 0 interventions.

NCT00340509 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00340509 about?

NCT00340509 is a clinical study titled "A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study". Studies have shown that there is a significant association between serum bilirubin concentrations and risk of coronary artery disease (CAD). So far, no linkage analysis in humans between serum bilirubin and DNA markers has been reported. The purpose of this protocol is to identify chromosome regions...

What is the current status of trial NCT00340509?

This trial is currently completed. The enrollment target is 1,888 participants. The study started on 2001-10-26. Estimated completion is 2013-07-23.

What conditions does trial NCT00340509 study?

This clinical trial studies the following conditions: Genetics.

Who is sponsoring clinical trial NCT00340509?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00340509 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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