Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00323531 · ClinicalTrials.gov registry record · Phase 2
Thoracoscopy Versus Fibrinolysis in Children With Empyema
A Phase 2 study of Empyema, sponsored by Children's Mercy Hospital Kansas City.
- Completed
- Registry status
- Phase 2
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT00323531: Completed Phase 2 study of Empyema, sponsored by Children's Mercy Hospital Kansas City.
NCT00323531 is a Phase 2 study of Empyema that has completed, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 36 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00323531, a Phase 2 study of Empyema, has completed, sponsored by Children's Mercy Hospital Kansas City.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The null hypothesis is that patients receiving either thoracoscopy or fibrinolysis for empyema recover in the same amount of time. Therefore, we will test this by randomizing the next 40 patients who consent to the study to one treatment or the other.
Conditions Studied
Interventions
- PROCEDURE Chest tube with tPA infusion for 3 days
- PROCEDURE VATS decortication
Study Locations (1)
Missouri
- Children's Mercy Hospital - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2006-03 |
| Est. Completion | 2007-10 |
| Phase | Phase 2 |
What the finished NCT00323531 record still lists
NCT00323531 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower).
The record links to 1 condition, with Empyema appearing as the primary indexed condition, and to 2 interventions - of which Chest tube with tPA infusion for 3 days is the first listed.
NCT00323531 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT00323531 about?
NCT00323531 is a clinical study titled "Thoracoscopy Versus Fibrinolysis in Children With Empyema". The null hypothesis is that patients receiving either thoracoscopy or fibrinolysis for empyema recover in the same amount of time. Therefore, we will test this by randomizing the next 40 patients who consent to the study to one treatment or the other.
What is the current status of trial NCT00323531?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2006-03. Estimated completion is 2007-10.
What conditions does trial NCT00323531 study?
This clinical trial studies the following conditions: Empyema.
What interventions are being tested in trial NCT00323531?
The interventions under investigation include: Chest tube with tPA infusion for 3 days (PROCEDURE), VATS decortication (PROCEDURE).
Who is sponsoring clinical trial NCT00323531?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00323531 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Empyema
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00323531's enrollment target sits among peer trials
36 1496th of 2000 higher than 477 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00929006 · 36 participants · Early Phase 1
Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
- NCT01891318 · 36 participants · Phase 1
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
- NCT02291848 · 36 participants · Phase 1
Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma
- NCT02366819 · 36 participants · Phase 4
Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia