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NCT00271492 · ClinicalTrials.gov registry record · Phase 3

Correlation of Endothelial Function and Early Coronary Artery Disease in Humans

A Phase 3 study of Endothelial Dysfunction, sponsored by Mayo Clinic.

Completed
Registry status
Phase 3
Development phase
200
Enrollment target
1
Study location

NCT00271492 is a Phase 3 study of Endothelial Dysfunction that has completed, run by Mayo Clinic. The registered enrollment target is 200 participants, above the 88-participant average among 45 other Endothelial Dysfunction trials with a reported enrollment target (127% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00271492, a Phase 3 study of Endothelial Dysfunction, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 3
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

Qualifying patients who are scheduled for angiogram with endothelial function testing are approached to participate in this protocol (consent form reviewed with patient). Those who are willing to participate will have additional measurements taken during their angiogram as part of this protocol. Patients who are diagnosed with Endothelial Dysfunction as a result of a clinically indicated angiogram will be eligible to participate in a 6 month medication trial (Atrasentan vs. placebo - randomized, blinded trial). Patients are monitored closely during the 6 month trial via phone calls and blood testing for assessment. At the end of the 6 months they return to Mayo for a repeat angiogram to assess endothelial function for any changes or improvements.

Conditions Studied

Interventions

  • DRUG Atrasentan
  • DRUG atrasentan

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2001-07
Est. Completion 2008-01
Phase Phase 3

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT00271492

The ClinicalTrials.gov registry entry for NCT00271492 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 88-participant average among 45 other Endothelial Dysfunction trials with a reported enrollment target (127% higher). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Endothelial Dysfunction appearing as the primary indexed condition, and to 2 interventions - of which Atrasentan is the first listed.

NCT00271492 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00271492 about?

NCT00271492 is a clinical study titled "Correlation of Endothelial Function and Early Coronary Artery Disease in Humans". Qualifying patients who are scheduled for angiogram with endothelial function testing are approached to participate in this protocol (consent form reviewed with patient). Those who are willing to participate will have additional measurements taken during their angiogram as part of this protocol. Pat...

What is the current status of trial NCT00271492?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 200 participants. The study started on 2001-07. Estimated completion is 2008-01.

What conditions does trial NCT00271492 study?

This clinical trial studies the following conditions: Endothelial Dysfunction.

What interventions are being tested in trial NCT00271492?

The interventions under investigation include: Atrasentan (DRUG), atrasentan (DRUG).

Who is sponsoring clinical trial NCT00271492?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00271492 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.