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NCT00217048 · ClinicalTrials.gov registry record · Phase 1
Effect of Yohimbine on Colon Transit
A Phase 1 study of Healthy Volunteers, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT00217048: Completed Phase 1 study of Healthy Volunteers, sponsored by Mayo Clinic.
NCT00217048 is a Phase 1 study of Healthy Volunteers that has completed, run by Mayo Clinic. The registered enrollment target is 30 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00217048, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to learn if yohimbine, a naturally occurring drug, affects the speed at which food travels through the stomach, intestines and colon, and if yohimbine affects the amount of liquid you can drink in a short period of time. Understanding how yohimbine works on the gut may help develop new treatments for patients with constipation. Yohimbine has been approved by the Food and Drug Administration (FDA) for routine clinical use, however, its use as proposed in this study is considered investigational.
Conditions Studied
Interventions
- DRUG Yohimbine, oral
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2005-06 |
| Est. Completion | 2005-10 |
| Phase | Phase 1 |
What the finished NCT00217048 record still lists
NCT00217048 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which Yohimbine, oral is the first listed.
NCT00217048 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT00217048 about?
NCT00217048 is a clinical study titled "Effect of Yohimbine on Colon Transit". This study is being done to learn if yohimbine, a naturally occurring drug, affects the speed at which food travels through the stomach, intestines and colon, and if yohimbine affects the amount of liquid you can drink in a short period of time. Understanding how yohimbine works on the gut may help ...
What is the current status of trial NCT00217048?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2005-06. Estimated completion is 2005-10.
What conditions does trial NCT00217048 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT00217048?
The interventions under investigation include: Yohimbine, oral (DRUG).
Who is sponsoring clinical trial NCT00217048?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00217048 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00217048's enrollment target sits among peer trials
30 187th of 283 higher than 87 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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