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NCT00129441 · ClinicalTrials.gov registry record · Phase 2
Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study
A Phase 2 study of Schizophrenia, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 2
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT00129441: Completed Phase 2 study of Schizophrenia, sponsored by University of Pittsburgh.
NCT00129441 is a Phase 2 study of Schizophrenia that has completed, run by University of Pittsburgh. The registered enrollment target is 16 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00129441, a Phase 2 study of Schizophrenia, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to determine whether a short-term administration of an investigational study drug may provide evidence of improvement in cognitive functioning in a group of stable male subjects with schizophrenia.
Primary Outcome
The N-back task is a sequential-letter memory task for which working memory load is varied, as the respondent must indicate when the current stimulus matches the one from 'n' steps earlier in the sequence. The dependent measure for the N-back task was performance in the 2-back condition, which provides the best index of performance and dorsolateral prefrontal cortex disturbances in subjects with schizophrenia.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Merck L-830982
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2005-08 |
| Est. Completion | 2008-01 |
| Phase | Phase 2 |
What the finished NCT00129441 record still lists
NCT00129441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00129441 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00129441 about?
NCT00129441 is a clinical study titled "Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study". The purpose of this research study is to determine whether a short-term administration of an investigational study drug may provide evidence of improvement in cognitive functioning in a group of stable male subjects with schizophrenia.
What is the current status of trial NCT00129441?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2005-08. Estimated completion is 2008-01.
What conditions does trial NCT00129441 study?
This clinical trial studies the following conditions: Schizophrenia.
What interventions are being tested in trial NCT00129441?
The interventions under investigation include: Placebo (DRUG), Merck L-830982 (DRUG).
Who is sponsoring clinical trial NCT00129441?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00129441 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00129441's enrollment target sits among peer trials
16 297th of 315 higher than 16 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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