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NCT00123708 · ClinicalTrials.gov registry record

Hypertonia in Patients With Cerebral Palsy

A clinical trial of Cerebral Palsy and Muscle Hypertonia, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Completed
Registry status
100
Enrollment target
1
Study location

NCT00123708 is a study of Cerebral Palsy and Muscle Hypertonia that has completed, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 100 participants, below the 228-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (56% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00123708, a study of Cerebral Palsy and Muscle Hypertonia, has completed, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

COMPLETED
Registry status
100 participants
Enrollment target
1
Study location

Study Summary

This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension. It is a common symptom of cerebral palsy that can lead to loss of function and deformity. This study may help scientists improve evaluation criteria for hypertonia and, ultimately, treatment results. Patients with cerebral palsy who are older than 6 years of age may be eligible for this study. Candidates are screened with a medical history and clinical evaluation. Participants are asked to walk in the lab while cameras record their movement. During this test, subjects wear a t-shirt and shorts with their arms and legs wrapped with a soft, rubber-like material. A piece of firm material is attached to the rubber sleeves and small plastic reflective balls are attached to the firm material. Balls may also be attached to the skin, using an adhesive. With the balls in place, the subject walks several times while cameras record the positions of the balls. In addition, small metal electrodes attached to the skin with an adhesive measure the electrical activity in the muscles. After the walking test is completed, subjects' leg muscle strength is measured with a special device while they perform three activities. First, they sit on a special chair with their leg and foot placed in an apparatus that measures their strength, then lie on their back, then on their stomach, and then stand on one foot holding a bar to balance during part of one activity. During the activities, their reflexes are tested, they are asked to move their legs, and their legs are moved for them.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2005-07-19

What the Registry Record Tells You About NCT00123708

The ClinicalTrials.gov registry entry for NCT00123708 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 228-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (56% lower). The listed sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cerebral Palsy appearing as the primary indexed condition, and to 0 interventions.

NCT00123708 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00123708 about?

NCT00123708 is a clinical study titled "Hypertonia in Patients With Cerebral Palsy". This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension. It is a common symptom of cerebral palsy that can lead to loss of func...

What is the current status of trial NCT00123708?

This trial is currently completed. The enrollment target is 100 participants. The study started on 2005-07-19.

What conditions does trial NCT00123708 study?

This clinical trial studies the following conditions: Cerebral Palsy, Muscle Hypertonia.

Who is sponsoring clinical trial NCT00123708?

This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00123708 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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