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NCT07433647 · ClinicalTrials.gov registry record
Evaluation of Brain MRI Changes in Cerebral Palsy Patients
A clinical trial of Cerebral Palsy and Spastic Diplegia, sponsored by Columbia University.
- Recruiting
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT07433647: Recruiting study of Cerebral Palsy and Spastic Diplegia, sponsored by Columbia University.
NCT07433647 is a study of Cerebral Palsy and Spastic Diplegia that is actively recruiting participants, run by Columbia University. The registered enrollment target is 30 participants, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07433647, a study of Cerebral Palsy and Spastic Diplegia, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain. A key part of the definition for CP is a non-progressive brain injury; however, as individuals with CP age, a functional decline greater than neurotypical individuals is often present. The investigators are doing this research study to improve understanding of whether there is brain and spinal cord atrophy over time that could indicate neurodegeneration. To do this, the investigators will partner with the Cerebral Palsy Research Network to obtain brain and spinal cord MRIs from people with CP across the United States. The investigators will perform analyses on multiple longitudinal MR images of the brain and spinal cord obtained from adults with CP. Putative changes will be related with changes in function across time. ... This will be a single-center study that will compare retrospective clinical and imaging data with similar prospective data. The objective is to find out if people with Cerebral Palsy (CP) experience changes in the structures of their brain over time. A key part of the CP definition is that it is a non-progressive brain injury. However, as people with CP age, their function often deteriorates. This study seeks to determine whether changes in the brain structure may result in function changes, as they do in other types of brain injuries. The investigators are doing this research study to improve understanding of whether there is brain and spinal cord atrophy over time that could indicate neurodegeneration. To do this, the investigators will partner with the Cerebral Palsy Research Network to obtain brain and spinal cord MRIs from people with CP across the United States, as well as locally. The investigators will perform analyses on multiple longitudinal MR images of the brain and spinal cord obtained from adults with CP. Putative changes will be related with changes in
Primary Outcome
This is a number, measured in cubic millimeters, that includes the output from segmentation of each individual MRI scan per subject.
Conditions Studied
Study Locations (1)
New York
- Weinberg Family Cerebral Palsy Center, Columbia University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-06-20 |
| Est. Completion | 2029-07-01 |
What NCT07433647 shows while recruiting
NCT07433647 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (87% lower).
The record links to 4 conditions, with Cerebral Palsy appearing as the primary indexed condition, and to 0 interventions.
NCT07433647 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07433647 about?
NCT07433647 is a clinical study titled "Evaluation of Brain MRI Changes in Cerebral Palsy Patients". Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain. A key part of the definition for CP is a non-progressive brain injury; however, as individuals with CP age, a functiona...
What is the current status of trial NCT07433647?
This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2023-06-20. Estimated completion is 2029-07-01.
What conditions does trial NCT07433647 study?
This clinical trial studies the following conditions: Cerebral Palsy, Spastic Diplegia, Spastic Quadriplegia, Spastic Hemiplegia.
Who is sponsoring clinical trial NCT07433647?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07433647 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07433647's enrollment target sits among peer trials
30 55th of 91 higher than 29 of 91 other Cerebral Palsy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cerebral Palsy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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