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NCT00078624 · ClinicalTrials.gov registry record · Phase 2
Knee Stability Training for Knee Osteoarthritis (OA)
A Phase 2 study of Osteoarthritis and Joint Diseases, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 2
- Development phase
- 231
- Enrollment target
- 1
- Study location
NCT00078624: Completed Phase 2 study of Osteoarthritis and Joint Diseases, sponsored by University of Pittsburgh.
NCT00078624 is a Phase 2 study of Osteoarthritis and Joint Diseases that has completed, run by University of Pittsburgh. The registered enrollment target is 231 participants, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00078624, a Phase 2 study of Osteoarthritis and Joint Diseases, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 231 participants
- Enrollment target
- 1
- Study location
Study Summary
People with knee osteoarthritis (OA) frequently complain of knee instability. This study will test whether certain exercises can improve knee stability, reduce pain, and improve physical function in people with knee OA. Study hypotheses: 1) Participants in the stability training group will demonstrate less pain and higher levels of physical function, based on self-report measures of pain and function (WOMAC, Lower Extremity Function Scale), and less time to complete the Get Up and Go test, a physical performance measure of function. 2) During walking and the step down task, participants in the stability training group will demonstrate greater knee motion during weight bearing, greater vertical ground reaction forces and loading rates, and reduced ratios of co-contraction between quadriceps/hamsting and tibialis anterior/gastrocnemius muscle pairs compared to the standard group. Participants in the stability group will also demonstrate greater step lengths, single limb support times, and average walking velocity compared to the standard group.
Conditions Studied
Interventions
- OTHER Traditional exercise therapy for knee osteoarthritis
- OTHER Knee stability training
Study Locations (1)
Pennsylvania
- University of Pittsburgh, Department of Physical Therapy, School of Health and Rehabilitation Sciences - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 231 participants |
| Start Date | 2004-04 |
| Est. Completion | 2008-12 |
| Phase | Phase 2 |
What the finished NCT00078624 record still lists
NCT00078624 is an interventional study that assigns participants to a tested intervention. The registered 231 participants enrollment target is mid-sized for trials with a published cap, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (72% lower).
The record links to 2 conditions, with Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Traditional exercise therapy for knee osteoarthritis is the first listed.
NCT00078624 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00078624 about?
NCT00078624 is a clinical study titled "Knee Stability Training for Knee Osteoarthritis (OA)". People with knee osteoarthritis (OA) frequently complain of knee instability. This study will test whether certain exercises can improve knee stability, reduce pain, and improve physical function in people with knee OA. Study hypotheses: 1) Participants in the stability training group will demonstr...
What is the current status of trial NCT00078624?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 231 participants. The study started on 2004-04. Estimated completion is 2008-12.
What conditions does trial NCT00078624 study?
This clinical trial studies the following conditions: Osteoarthritis, Joint Diseases.
What interventions are being tested in trial NCT00078624?
The interventions under investigation include: Traditional exercise therapy for knee osteoarthritis (OTHER), Knee stability training (OTHER).
Who is sponsoring clinical trial NCT00078624?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00078624 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00078624's enrollment target sits among peer trials
231 49th of 135 higher than 86 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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