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NCT00078624 · ClinicalTrials.gov registry record · Phase 2

Knee Stability Training for Knee Osteoarthritis (OA)

A Phase 2 study of Osteoarthritis and Joint Diseases, sponsored by University of Pittsburgh.

Completed
Registry status
Phase 2
Development phase
231
Enrollment target
1
Study location

NCT00078624 is a Phase 2 study of Osteoarthritis and Joint Diseases that has completed, run by University of Pittsburgh. The registered enrollment target is 231 participants, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00078624, a Phase 2 study of Osteoarthritis and Joint Diseases, has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
Phase 2
Development phase
231 participants
Enrollment target
1
Study location

Study Summary

People with knee osteoarthritis (OA) frequently complain of knee instability. This study will test whether certain exercises can improve knee stability, reduce pain, and improve physical function in people with knee OA. Study hypotheses: 1) Participants in the stability training group will demonstrate less pain and higher levels of physical function, based on self-report measures of pain and function (WOMAC, Lower Extremity Function Scale), and less time to complete the Get Up and Go test, a physical performance measure of function. 2) During walking and the step down task, participants in the stability training group will demonstrate greater knee motion during weight bearing, greater vertical ground reaction forces and loading rates, and reduced ratios of co-contraction between quadriceps/hamsting and tibialis anterior/gastrocnemius muscle pairs compared to the standard group. Participants in the stability group will also demonstrate greater step lengths, single limb support times, and average walking velocity compared to the standard group.

Interventions

  • OTHER Traditional exercise therapy for knee osteoarthritis
  • OTHER Knee stability training

Study Locations (1)

Pennsylvania

  • University of Pittsburgh, Department of Physical Therapy, School of Health and Rehabilitation Sciences - Pittsburgh

Trial Details

FieldValue
Enrollment Target 231 participants
Start Date 2004-04
Est. Completion 2008-12
Phase Phase 2

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT00078624

The ClinicalTrials.gov registry entry for NCT00078624 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 231 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (72% lower). The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Traditional exercise therapy for knee osteoarthritis is the first listed.

NCT00078624 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00078624 about?

NCT00078624 is a clinical study titled "Knee Stability Training for Knee Osteoarthritis (OA)". People with knee osteoarthritis (OA) frequently complain of knee instability. This study will test whether certain exercises can improve knee stability, reduce pain, and improve physical function in people with knee OA. Study hypotheses: 1) Participants in the stability training group will demonstr...

What is the current status of trial NCT00078624?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 231 participants. The study started on 2004-04. Estimated completion is 2008-12.

What conditions does trial NCT00078624 study?

This clinical trial studies the following conditions: Osteoarthritis, Joint Diseases.

What interventions are being tested in trial NCT00078624?

The interventions under investigation include: Traditional exercise therapy for knee osteoarthritis (OTHER), Knee stability training (OTHER).

Who is sponsoring clinical trial NCT00078624?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00078624 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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