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NCT00073957 · ClinicalTrials.gov registry record · Phase 2

Y 90 Ibritumomab Tiuxetan &Rituximab Relapsed or Refractory Diffuse Large B-Cell Non-Hodgkin's Lymphoma

A Phase 2 study of Lymphoma, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target
2
Study locations

NCT00073957 is a Phase 2 study of Lymphoma that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 25 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00073957, a Phase 2 study of Lymphoma, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan and rituximab, can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Combining yttrium Y 90 ibritumomab tiuxetan with rituximab may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining yttrium Y 90 Ibritumomab tiuxetan with rituximab in treating patients who have relapsed or refractory diffuse large B-cell non-Hodgkin's lymphoma.

Conditions Studied

Interventions

  • BIOLOGICAL rituximab
  • DRUG cytarabine
  • DRUG liposomal cytarabine
  • RADIATION yttrium Y 90 ibritumomab tiuxetan

Study Locations (2)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Vermont

  • Fletcher Allen Health Care - Medical Center Campus - Burlington

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2003-12
Est. Completion 2012-01-01
Phase Phase 2

What the Registry Record Tells You About NCT00073957

The ClinicalTrials.gov registry entry for NCT00073957 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (95% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lymphoma appearing as the primary indexed condition, and to 4 interventions - of which rituximab is the first listed.

NCT00073957 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Massachusetts, Vermont.

Frequently Asked Questions

What is clinical trial NCT00073957 about?

NCT00073957 is a clinical study titled "Y 90 Ibritumomab Tiuxetan &Rituximab Relapsed or Refractory Diffuse Large B-Cell Non-Hodgkin's Lymphoma". RATIONALE: Monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan and rituximab, can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Combining yttrium Y 90 ibritumomab tiuxetan with rituximab may kill more canc...

What is the current status of trial NCT00073957?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2003-12. Estimated completion is 2012-01-01.

What conditions does trial NCT00073957 study?

This clinical trial studies the following conditions: Lymphoma.

What interventions are being tested in trial NCT00073957?

The interventions under investigation include: rituximab (BIOLOGICAL), cytarabine (DRUG), liposomal cytarabine (DRUG), yttrium Y 90 ibritumomab tiuxetan (RADIATION).

Who is sponsoring clinical trial NCT00073957?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00073957 being conducted?

This trial has 2 study locations across Massachusetts, Vermont. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.