Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00018473 · ClinicalTrials.gov registry record
Gene-Environment Interactions in Alzheimer's Disease
A clinical trial of Alzheimers Disease, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- 1
- Study location
NCT00018473: Completed study of Alzheimers Disease, sponsored by US Department of Veterans Affairs.
NCT00018473 is a study of Alzheimers Disease that has completed, run by US Department of Veterans Affairs. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00018473, a study of Alzheimers Disease, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- 1
- Study location
Study Summary
This study will create Alzheimer 's disease risk profiles for defined combinations of genotypes and environmental exposures. This study will carry out a molecular epidemiologic study to identify genetic and environmental risks factors using state of the art techniques. The following will be done during the course of this study 1) Recruit both Alzheimer's patients and cognitively normal aged veterans. 2) Evaluate gene interaction in Alzheimer's disease. 3) Evaluate gene-environment interactions on the risk of Alzheimer's disease. These procedures should initially address the question as to whether certain genes either independently or synergistically modify the risk of Alzheimer's disease. This study will also determine whether certain environmental factors (smoking, alcohol consumption etc.) can modify the risk of AD and whether this effect is dependent on certain genetic backgrounds. This study will provide information that will be useful in designing therapies, develop risk factor profiles to be further tested in future studies, designating patients for specific therapies based on genetic factors and providing data and genetic material for future studies. This study will also provide a cohort of older and well characterized cognitively normal veterans for prospective genetic epidemiological studies on aging.
Conditions Studied
Study Locations (1)
Massachusetts
- VAMC- Bedford (Station 518) - Bedford
Trial Details
| Field | Value |
|---|---|
| Start Date | 1999-04 |
| Est. Completion | 2004-03 |
What the finished NCT00018473 record still lists
NCT00018473 is an observational study that tracks outcomes without assigning an intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 0 interventions.
NCT00018473 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00018473 about?
NCT00018473 is a clinical study titled "Gene-Environment Interactions in Alzheimer's Disease". This study will create Alzheimer 's disease risk profiles for defined combinations of genotypes and environmental exposures. This study will carry out a molecular epidemiologic study to identify genetic and environmental risks factors using state of the art techniques. The following will be done dur...
What is the current status of trial NCT00018473?
This trial is currently completed. The study started on 1999-04. Estimated completion is 2004-03.
What conditions does trial NCT00018473 study?
This clinical trial studies the following conditions: Alzheimers Disease.
Who is sponsoring clinical trial NCT00018473?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00018473 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimers Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
RECRUITING · Phase 3
-
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
RECRUITING · Phase 2
-
University of Central Florida Music Study
RECRUITING · NA
-
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
RECRUITING · Phase 2
-
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
RECRUITING · Phase 3
-
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
RECRUITING · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia