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NCT00018473 · ClinicalTrials.gov registry record

Gene-Environment Interactions in Alzheimer's Disease

A clinical trial of Alzheimers Disease, sponsored by US Department of Veterans Affairs.

Completed
Registry status
1
Study location

NCT00018473 is a study of Alzheimers Disease that has completed, run by US Department of Veterans Affairs. The trial reports 1 study location across 1 state.

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The verdict

NCT00018473, a study of Alzheimers Disease, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
1
Study location

Study Summary

This study will create Alzheimer 's disease risk profiles for defined combinations of genotypes and environmental exposures. This study will carry out a molecular epidemiologic study to identify genetic and environmental risks factors using state of the art techniques. The following will be done during the course of this study 1) Recruit both Alzheimer's patients and cognitively normal aged veterans. 2) Evaluate gene interaction in Alzheimer's disease. 3) Evaluate gene-environment interactions on the risk of Alzheimer's disease. These procedures should initially address the question as to whether certain genes either independently or synergistically modify the risk of Alzheimer's disease. This study will also determine whether certain environmental factors (smoking, alcohol consumption etc.) can modify the risk of AD and whether this effect is dependent on certain genetic backgrounds. This study will provide information that will be useful in designing therapies, develop risk factor profiles to be further tested in future studies, designating patients for specific therapies based on genetic factors and providing data and genetic material for future studies. This study will also provide a cohort of older and well characterized cognitively normal veterans for prospective genetic epidemiological studies on aging.

Conditions Studied

Study Locations (1)

Massachusetts

  • VAMC- Bedford (Station 518) - Bedford

Trial Details

FieldValue
Start Date 1999-04
Est. Completion 2004-03

Sponsor

US Department of Veterans Affairs

632 total trials

What the Registry Record Tells You About NCT00018473

The ClinicalTrials.gov registry entry for NCT00018473 describes a study currently listed as completed, categorized as an unspecified phase. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is US Department of Veterans Affairs, which has 632 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 0 interventions.

NCT00018473 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00018473 about?

NCT00018473 is a clinical study titled "Gene-Environment Interactions in Alzheimer's Disease". This study will create Alzheimer 's disease risk profiles for defined combinations of genotypes and environmental exposures. This study will carry out a molecular epidemiologic study to identify genetic and environmental risks factors using state of the art techniques. The following will be done dur...

What is the current status of trial NCT00018473?

This trial is currently completed. The study started on 1999-04. Estimated completion is 2004-03.

What conditions does trial NCT00018473 study?

This clinical trial studies the following conditions: Alzheimers Disease.

Who is sponsoring clinical trial NCT00018473?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00018473 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.