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NCT07170150 · ClinicalTrials.gov registry record · Phase 3
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
A Phase 3 study of Alzheimers Disease, sponsored by Hoffmann-La Roche.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 800
- Enrollment target
- 20
- Study locations
NCT07170150: Recruiting Phase 3 study of Alzheimers Disease, sponsored by Hoffmann-La Roche.
NCT07170150 is a Phase 3 study of Alzheimers Disease that is actively recruiting participants, run by Hoffmann-La Roche. The registered enrollment target is 800 participants, below the 3,921-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (80% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07170150, a Phase 3 study of Alzheimers Disease, is actively recruiting participants, sponsored by Hoffmann-La Roche.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 800 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Trontinemab
Study Locations (20)
Florida
- JEM Research LLC - Atlantis
- K2 Medical Research-Winter Garden - Clermont
- Visionary Investigators Network- Neurology Aventura - Miami
- Charter Research - Winter Park/Orlando - Orlando
- Conquest Research - Lake Nona - Orlando
- Alzheimer's Research and Treatment Center - Stuart
California
- Sun Valley Research Center, Inc. - Imperial
- Healthy Brain Clinic - Long Beach
- Oakland Clinical - Oakland
- Riverside Clinical - Riverside
- Cenexel California Neuroscience Research, LLC - Sherman Oaks
Georgia
- CenExel iResearch, LLC - Decatur
- Center for Advanced Research & Education - Gainesville
Arizona
- Banner Alzheimer?s Institute - Phoenix
Connecticut
- Yale University - New Haven
Illinois
- Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville - Chicago
Massachusetts
- Adams Clinical Watertown - Watertown
Michigan
- Quest Research Institute - Farmington Hills
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2025-11-12 |
| Est. Completion | 2028-06-07 |
| Phase | Phase 3 |
What NCT07170150 shows while recruiting
NCT07170150 is an interventional study that assigns participants to a tested intervention. The registered 800 participants enrollment target is mid-sized for trials with a published cap, below the 3,921-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07170150 names 20 study sites across 10 states, led by Florida, California, Georgia.
Frequently Asked Questions
What is clinical trial NCT07170150 about?
NCT07170150 is a clinical study titled "A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease". The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).
What is the current status of trial NCT07170150?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 800 participants. The study started on 2025-11-12. Estimated completion is 2028-06-07.
What conditions does trial NCT07170150 study?
This clinical trial studies the following conditions: Alzheimers Disease.
What interventions are being tested in trial NCT07170150?
The interventions under investigation include: Placebo (OTHER), Trontinemab (DRUG).
Who is sponsoring clinical trial NCT07170150?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07170150 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimers Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07170150's enrollment target sits among peer trials
800 19th of 147 higher than 127 of 147 other Alzheimers Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimers Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
RECRUITING · Phase 3
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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
RECRUITING · Phase 3
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A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)
ACTIVE NOT RECRUITING · Phase 3
-
A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)
ACTIVE NOT RECRUITING · Phase 3
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