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NCT07170150 · ClinicalTrials.gov registry record · Phase 3

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

A Phase 3 study of Alzheimers Disease, sponsored by Hoffmann-La Roche.

Recruiting
Registry status
Phase 3
Development phase
800
Enrollment target
20
Study locations

NCT07170150 is a Phase 3 study of Alzheimers Disease that is actively recruiting participants, run by Hoffmann-La Roche. The registered enrollment target is 800 participants, below the 4,056-participant average among 142 other Alzheimers Disease trials with a reported enrollment target (80% lower). The trial reports 20 study locations across 10 states.

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The verdict

NCT07170150, a Phase 3 study of Alzheimers Disease, is actively recruiting participants, sponsored by Hoffmann-La Roche.

RECRUITING
Registry status
Phase 3
Development phase
800 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Trontinemab

Study Locations (20)

Florida

  • JEM Research LLC - Atlantis
  • K2 Medical Research-Winter Garden - Clermont
  • Visionary Investigators Network- Neurology Aventura - Miami
  • Charter Research - Winter Park/Orlando - Orlando
  • Conquest Research - Lake Nona - Orlando
  • Alzheimer's Research and Treatment Center - Stuart

California

  • Sun Valley Research Center, Inc. - Imperial
  • Healthy Brain Clinic - Long Beach
  • Oakland Clinical - Oakland
  • Riverside Clinical - Riverside
  • Cenexel California Neuroscience Research, LLC - Sherman Oaks

Georgia

  • CenExel iResearch, LLC - Decatur
  • Center for Advanced Research & Education - Gainesville

Arizona

  • Banner Alzheimer?s Institute - Phoenix

Connecticut

  • Yale University - New Haven

Illinois

  • Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville - Chicago

Massachusetts

  • Adams Clinical Watertown - Watertown

Michigan

  • Quest Research Institute - Farmington Hills

Trial Details

FieldValue
Enrollment Target 800 participants
Start Date 2025-11-12
Est. Completion 2028-06-07
Phase Phase 3

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT07170150

The ClinicalTrials.gov registry entry for NCT07170150 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,056-participant average among 142 other Alzheimers Disease trials with a reported enrollment target (80% lower). The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07170150 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Florida, California, Georgia.

Frequently Asked Questions

What is clinical trial NCT07170150 about?

NCT07170150 is a clinical study titled "A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease". The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).

What is the current status of trial NCT07170150?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 800 participants. The study started on 2025-11-12. Estimated completion is 2028-06-07.

What conditions does trial NCT07170150 study?

This clinical trial studies the following conditions: Alzheimers Disease.

What interventions are being tested in trial NCT07170150?

The interventions under investigation include: Placebo (OTHER), Trontinemab (DRUG).

Who is sponsoring clinical trial NCT07170150?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07170150 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.