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NCT00003895 · ClinicalTrials.gov registry record · Phase 2

Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma

A Phase 2 study of Recurrent Melanoma and Stage IIIC Melanoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
36
Enrollment target
1
Study location

NCT00003895 is a Phase 2 study of Recurrent Melanoma and Stage IIIC Melanoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 36 participants, below the 171-participant average among 23 other Recurrent Melanoma trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00003895, a Phase 2 study of Recurrent Melanoma and Stage IIIC Melanoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

This randomized pilot phase II trial studies how well vaccine therapy works in treating human leukocyte antigen class 1 histocompatibility, A-2 (HLA-A2) positive patients with melanoma. Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.

Interventions

  • OTHER laboratory biomarker analysis
  • BIOLOGICAL HPV 16 E7:12-20
  • BIOLOGICAL gp100:209-217(210M)

Study Locations (1)

Oregon

  • Providence Portland Medical Center - Portland

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 1999-04
Est. Completion 2013-09
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00003895

The ClinicalTrials.gov registry entry for NCT00003895 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 171-participant average among 23 other Recurrent Melanoma trials with a reported enrollment target (79% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Recurrent Melanoma appearing as the primary indexed condition, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT00003895 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT00003895 about?

NCT00003895 is a clinical study titled "Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma". This randomized pilot phase II trial studies how well vaccine therapy works in treating human leukocyte antigen class 1 histocompatibility, A-2 (HLA-A2) positive patients with melanoma. Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.

What is the current status of trial NCT00003895?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 1999-04. Estimated completion is 2013-09.

What conditions does trial NCT00003895 study?

This clinical trial studies the following conditions: Recurrent Melanoma, Stage IIIC Melanoma, Stage IA Melanoma, Stage IB Melanoma, Stage IIA Melanoma.

What interventions are being tested in trial NCT00003895?

The interventions under investigation include: laboratory biomarker analysis (OTHER), HPV 16 E7:12-20 (BIOLOGICAL), gp100:209-217(210M) (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003895?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00003895 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.