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NCT00003582 · ClinicalTrials.gov registry record · Phase 1
Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer
A Phase 1 study of Head and Neck Cancer and Carcinoma of Unknown Primary, sponsored by University of Miami.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT00003582 is a Phase 1 study of Head and Neck Cancer and Carcinoma of Unknown Primary that has completed, run by University of Miami. The registered enrollment target is 36 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00003582, a Phase 1 study of Head and Neck Cancer and Carcinoma of Unknown Primary, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of radiation therapy and chemotherapy. PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy plus combination chemotherapy and amifostine in treating patients who have stage II, stage III, or stage IV head and neck cancer that cannot be surgically removed.
Conditions Studied
Interventions
- DRUG cisplatin
- DRUG paclitaxel
- PROCEDURE quality-of-life assessment
- DRUG fluorouracil
- DRUG amifostine trihydrate
Study Locations (1)
Florida
- Sylvester Cancer Center, University of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 1988-05 |
| Est. Completion | 1996-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00003582
The ClinicalTrials.gov registry entry for NCT00003582 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (86% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 5 interventions - of which cisplatin is the first listed.
NCT00003582 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT00003582 about?
NCT00003582 is a clinical study titled "Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of radiation therapy and ...
What is the current status of trial NCT00003582?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 1988-05. Estimated completion is 1996-12.
What conditions does trial NCT00003582 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Carcinoma of Unknown Primary.
What interventions are being tested in trial NCT00003582?
The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), quality-of-life assessment (PROCEDURE), fluorouracil (DRUG), amifostine trihydrate (DRUG).
Who is sponsoring clinical trial NCT00003582?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00003582 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.