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NCT00003211 · ClinicalTrials.gov registry record · Phase 2
Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
A Phase 2 study of Brain and Central Nervous System Tumors, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 94
- Enrollment target
- 4
- Study locations
NCT00003211: Completed Phase 2 study of Brain and Central Nervous System Tumors, sponsored by St. Jude Children's Research Hospital.
NCT00003211 is a Phase 2 study of Brain and Central Nervous System Tumors that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 94 participants, below the 182-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (48% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003211, a Phase 2 study of Brain and Central Nervous System Tumors, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 94 participants
- Enrollment target
- 4
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy and radiation therapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy or radiation therapy and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with topotecan, cyclophosphamide, cisplatin, and vincristine plus radiation therapy and peripheral stem cell transplantation in treating children with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor.
Conditions Studied
Interventions
- DRUG cisplatin
- DRUG cyclophosphamide
- BIOLOGICAL filgrastim
- DRUG amifostine trihydrate
- DRUG vincristine sulfate
Study Locations (4)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Texas
- Texas Children's Cancer Center - Houston
New South Wales
- Children's Hospital at Westmead - Westmead
Victoria
- Royal Children's Hospital - Parkville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 94 participants |
| Start Date | 1996-10 |
| Est. Completion | 2007-06 |
| Phase | Phase 2 |
What the finished NCT00003211 record still lists
NCT00003211 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 94 participants, a relatively small participant target, below the 182-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (48% lower).
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 5 interventions - of which cisplatin is the first listed.
NCT00003211 reports a single indexed study location in Tennessee, Texas, New South Wales.
Frequently Asked Questions
What is clinical trial NCT00003211 about?
NCT00003211 is a clinical study titled "Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy and radiation therapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy or radiation therapy and kill more ...
What is the current status of trial NCT00003211?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 94 participants. The study started on 1996-10. Estimated completion is 2007-06.
What conditions does trial NCT00003211 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.
What interventions are being tested in trial NCT00003211?
The interventions under investigation include: cisplatin (DRUG), cyclophosphamide (DRUG), filgrastim (BIOLOGICAL), amifostine trihydrate (DRUG), vincristine sulfate (DRUG).
Who is sponsoring clinical trial NCT00003211?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00003211 being conducted?
This trial has 4 study locations across Tennessee, Texas, New South Wales, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain and Central Nervous System Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00003211's enrollment target sits among peer trials
94 15th of 45 higher than 31 of 45 other Brain and Central Nervous System Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain and Central Nervous System Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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