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NCT00001572 · ClinicalTrials.gov registry record · Phase 1

Vaccination of Follicular Lymphomas With Tumor-Derived Immunoglobulin Idiotype

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
21
Enrollment target

NCT00001572: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00001572 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 21 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00001572, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
21 participants
Enrollment target

Study Summary

Patients undergo chemotherapy until remission is obtained, or disease has been stable for two cycles of chemotherapy, or progressive disease develops. Three to six months after completion of chemotherapy, patients who have achieved complete clinical remission or minimal disease status receive a series of 5 injections (given 1-2 months apart) of a vaccine consisting of 0.5 mg autologous tumor-derived immunoglobulin (Id) conjugated to KLH. The vaccine is administered with subcutaneous QS-21 as an immunological adjuvant....

Interventions

  • DRUG Id-KLH Vaccine
  • DRUG QS-21 (Stimulation-QS-21) Drug

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 1997-01-30
Est. Completion 2010-11-02
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00001572 record still lists

NCT00001572 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 2 interventions - of which Id-KLH Vaccine is the first listed.

NCT00001572 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00001572 about?

NCT00001572 is a clinical study titled "Vaccination of Follicular Lymphomas With Tumor-Derived Immunoglobulin Idiotype". Patients undergo chemotherapy until remission is obtained, or disease has been stable for two cycles of chemotherapy, or progressive disease develops. Three to six months after completion of chemotherapy, patients who have achieved complete clinical remission or minimal disease status receive a ser...

What is the current status of trial NCT00001572?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 1997-01-30. Estimated completion is 2010-11-02.

What interventions are being tested in trial NCT00001572?

The interventions under investigation include: Id-KLH Vaccine (DRUG), QS-21 (Stimulation-QS-21) Drug (DRUG).

Who is sponsoring clinical trial NCT00001572?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00001572's enrollment target sits among peer trials

21 1615th of 2000 higher than 372 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00001572, the US trial registry maintained by the National Library of Medicine. NCT00001572 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.