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NCT00001327 · ClinicalTrials.gov registry record
Establishing the Physiology of Syringomyelia
A clinical trial of Hydrocephalus and Syringomyelia, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 120
- Enrollment target
- 1
- Study location
NCT00001327: Completed study of Hydrocephalus and Syringomyelia, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00001327 is a study of Hydrocephalus and Syringomyelia that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 120 participants, roughly in line with the 126-participant average among 17 other Hydrocephalus trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001327, a study of Hydrocephalus and Syringomyelia, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The brain and spinal cord are surrounded by fluid called cerebrospinal fluid (CSF). The CSF flows through channels in the brain and around the spinal cord. Occasionally, people are born with malformations of these channels. Syringomyelia is a pocket within the CSF channels that results from abnormal CSF flow. Syringomyelia is associated with problems in the nervous system. Patients with syringomyelia may be unable to detect sensations of pain and heat. If the condition is not treated it can worsen. Treatment of this condition is surgical. It requires that the flow of CSF is returns to normal. There are many different treatment options, but no one procedure has been shown to be significantly better than any other. In this study, researchers would like to learn more about how the CSF pressure and flow contribute to the progression of syringomyelia. Ultrasounds and magnetic resonance imaging (MRI) will be used to evaluate the anatomy of the brain. Researchers hope that information gathered about anatomy and measures of CSF pressure and flow can be used later to develop an optimal surgical treatment for syringomyelia.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 1992-07-29 |
| Est. Completion | 2011-03-31 |
What the finished NCT00001327 record still lists
NCT00001327 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 126-participant average among 17 other Hydrocephalus trials with a reported enrollment target.
The record links to 3 conditions, with Hydrocephalus appearing as the primary indexed condition, and to 0 interventions.
NCT00001327 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001327 about?
NCT00001327 is a clinical study titled "Establishing the Physiology of Syringomyelia". The brain and spinal cord are surrounded by fluid called cerebrospinal fluid (CSF). The CSF flows through channels in the brain and around the spinal cord. Occasionally, people are born with malformations of these channels. Syringomyelia is a pocket within the CSF channels that results from abnormal...
What is the current status of trial NCT00001327?
This trial is currently completed. The enrollment target is 120 participants. The study started on 1992-07-29. Estimated completion is 2011-03-31.
What conditions does trial NCT00001327 study?
This clinical trial studies the following conditions: Hydrocephalus, Syringomyelia, Arnold Chiari Deformity.
Who is sponsoring clinical trial NCT00001327?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001327 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hydrocephalus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00001327's enrollment target sits among peer trials
120 7th of 17 higher than 11 of 17 other Hydrocephalus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hydrocephalus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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