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NCT00001238 · ClinicalTrials.gov registry record

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

A clinical trial of Renal Cell Carcinoma and Kidney Cancer, sponsored by National Cancer Institute (NCI).

Recruiting
Registry status
5,000
Enrollment target
1
Study location

NCT00001238: Recruiting study of Renal Cell Carcinoma and Kidney Cancer, sponsored by National Cancer Institute (NCI).

NCT00001238 is a study of Renal Cell Carcinoma and Kidney Cancer that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 5,000 participants, above the 202-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (2375% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001238, a study of Renal Cell Carcinoma and Kidney Cancer, is actively recruiting participants, sponsored by National Cancer Institute (NCI).

RECRUITING
Registry status
5,000 participants
Enrollment target
1
Study location

Study Summary

We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled. Affected individuals or individuals suspected of having a germline urologic malignant disorder will undergo periodic clinical assessment and genetic analyses for the purpose of: 1) definition and characterization of phenotype, 2) determination of the natural history of the disorder, and 3) genotype/phenotype correlation. Genetic linkage studies may be performed in situations in which the genetic basis of the disorder has not been elucidated.

Primary Outcome

Collection of blood, tissue \& urine to address further scientific questions related to this protocol.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 5,000 participants
Start Date 1990-12-05
National Cancer Institute (NCI)

3,257 total trials

What NCT00001238 shows while recruiting

NCT00001238 is an observational study that tracks outcomes without assigning an intervention. Its 5,000 participants enrollment target places it among the larger protocols in the corpus, above the 202-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (2375% higher).

The record links to 5 conditions, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 0 interventions.

NCT00001238 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00001238 about?

NCT00001238 is a clinical study titled "Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders". We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled. Affected individuals or individuals suspected of having a germline urologic malignant dis...

What is the current status of trial NCT00001238?

This trial is currently recruiting. The enrollment target is 5,000 participants. The study started on 1990-12-05.

What conditions does trial NCT00001238 study?

This clinical trial studies the following conditions: Renal Cell Carcinoma, Kidney Cancer, Urologic Malignant Disorders, Familial Renal Cancer (FRC), Clear Cell Renal Cancer.

Who is sponsoring clinical trial NCT00001238?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001238 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Renal Cell Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001238's enrollment target sits among peer trials

5,000 1st of 121 higher than 121 of 121 other Renal Cell Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Renal Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00001238, the US trial registry maintained by the National Library of Medicine. NCT00001238 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.