Prelude Therapeutics

12 total trials 1 currently recruiting 8 completed

Prelude Therapeutics sponsors 12 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 8 completed. 0 of these trials are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Recurrent Glioma, with 1 trials.

Trial Pipeline

12 total, page 1 of 1

RECRUITING Phase 1

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

NCT07469891

TERMINATED Phase 2

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT06682806

TERMINATED Phase 1

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT06560645

COMPLETED Phase 1

A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

NCT05665530

COMPLETED Phase 1

PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation

NCT05639751

COMPLETED Phase 1

A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

NCT05538572

TERMINATED Phase 1

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

NCT05107856

COMPLETED Phase 1

A Study of PRT2527 in Participants With Advanced Solid Tumors

NCT05159518

COMPLETED Phase 1

A Study of PRT1419 in Patients With Advanced Solid Tumors

NCT04837677

COMPLETED Phase 1

A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic Malignancies

NCT04543305

COMPLETED Phase 1

A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas

NCT04089449

COMPLETED Phase 1

A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies

NCT03886831

Phase Distribution

PhaseTrial count
Phase 1 11
Phase 2 1

Therapeutic Areas

What the Pipeline for Prelude Therapeutics Shows

According to the ClinicalTrials.gov registry, Prelude Therapeutics is linked to 12 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 8 are already marked complete, representing roughly 67% of the total.

The phase mix for Prelude Therapeutics reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 12 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Prelude Therapeutics is Recurrent Glioma with 1 linked trial, and 1 other condition area appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.