National Cancer Institute (NCI)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Cancer Institute (NCI) sits in the top decile of US sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count).

3,257 total trials 326 currently recruiting 2051 completed early-phase tilt top decile by trial count

National Cancer Institute (NCI): 3,257 sponsored US clinical trials, 326 recruiting.

National Cancer Institute (NCI) sponsors 3,257 registered US clinical trials on ClinicalTrials.gov, 326 of them currently recruiting, and 2,051 completed. 193 of these trials are in Phase 3-4 (later-stage) and 2,628 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Malignant Solid Neoplasm, with 67 trials.

Top-decile sponsor footprint

National Cancer Institute (NCI) ranks in the top decile of sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

3,257 total, page 51 of 66

COMPLETED Phase 1

Oblimersen in Treating Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia

NCT00062244

COMPLETED Phase 2

Erlotinib in Treating Patients With Locally Advanced or Metastatic Papillary Renal Cell Cancer

NCT00060307

COMPLETED Phase 2

Romidepsin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00062075

COMPLETED

Markers for Early Detection of Prostate Cancer

NCT00340717

COMPLETED Phase 2

Imatinib Mesylate in Treating Patients With Recurrent Small Cell Lung Cancer

NCT00052949

TERMINATED Phase 2

Perifosine in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

NCT00062387

TERMINATED Phase 1

Oblimersen Plus Doxorubicin and Docetaxel in Treating Patients With Metastatic or Locally Advanced Breast Cancer

NCT00063934

COMPLETED

Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease

NCT00062166

COMPLETED

Studying Normal Breast Tissue and Cancer Risk

NCT00341692

COMPLETED

Cancer Risk in Carriers of the Gene for Xeroderma Pigmentosum

NCT00046189

COMPLETED Phase 2

Erlotinib Plus Carboplatin and Paclitaxel in Ovarian Carcinoma

NCT00059787

COMPLETED Phase 3

Anidulafungin Versus Fluconazole in the Treatment of Candidemia

NCT00058682

COMPLETED Phase 1

Celecoxib in Treating Postmenopausal Women Who Are Undergoing Surgery for Invasive Breast Cancer

NCT00070057

COMPLETED Phase 2

Carboplatin and Etoposide With or Without Oblimersen Sodium in Treating Patients With Extensive Stage Small Cell Lung Cancer

NCT00042978

COMPLETED Phase 1

Flavopiridol in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma

NCT00058240

COMPLETED Phase 2

Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach

NCT00061932

COMPLETED Phase 1

Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer

NCT00060372

COMPLETED Phase 1

Irinotecan and Thalidomide in Treating Patients With Advanced Solid Tumors

NCT00062127

COMPLETED Phase 1

Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma

NCT00058227

COMPLETED Phase 2

Peptide Vaccination for Patients at High Risk for Recurrent Melanoma

NCT00059475

COMPLETED Phase 1

Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Neck

NCT00063895

COMPLETED

Follow-up of Breast Cancer and Multiple Myeloma Patients Previously Enrolled in NIH Gene Therapy Studies

NCT00427726

COMPLETED NA

Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation

NCT00060021

COMPLETED Phase 2

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

NCT00058305

COMPLETED Phase 1

Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

NCT00055913

COMPLETED Phase 2

Combination Chemotherapy and Rituximab in Treating Patients With HIV-Associated Stage I, Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma

NCT00049036

COMPLETED Phase 2

Ixabepilone Compared With Mitoxantrone and Prednisone in Treating Patients With Refractory Metastatic Prostate Cancer

NCT00058084

TERMINATED Phase 1

Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma

NCT00060112

TERMINATED Phase 2

Perifosine in Treating Patients With Recurrent Prostate Cancer

NCT00058214

TERMINATED Phase 2

A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's Sarcoma

NCT00020683

COMPLETED Phase 2

Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients

NCT00055237

COMPLETED

High-Risk Breast Duct Epithelium

NCT00028340

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors

NCT00058253

COMPLETED Phase 2

Bevacizumab in Treating Patients With Unresectable Nonmetastatic Liver Cancer

NCT00055692

COMPLETED Phase 1

Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma

NCT00058279

COMPLETED Phase 3

Tamoxifen Compared With Thalidomide in Treating Women With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

NCT00041080

COMPLETED Phase 2

Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer

NCT00049114

COMPLETED Phase 2

Imatinib Mesylate in Treating Patients With Recurrent Meningioma

NCT00045734

COMPLETED Phase 2

PS-341 Alone and PS-341 Plus EPOCH Chemotherapy to Treat Non-Hodgkin's Lymphoma

NCT00054665

COMPLETED Phase 2

Ixabepilone in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

NCT00058019

COMPLETED

Cause of Familial Testicular Cancer

NCT00034424

COMPLETED

Study of Health Effects of Cosmetic Breast Augmentation

NCT00342953

COMPLETED Phase 2

Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers

NCT00051311

COMPLETED Phase 2

Imatinib Mesylate and Decitabine in Treating Patients With Chronic Myelogenous Leukemia

NCT00054431

COMPLETED Phase 2

Oxaliplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Cervical Cancer

NCT00057863

COMPLETED Phase 2

Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors

NCT00055809

COMPLETED Phase 3

Debulking and Chemotherapy With or Without Intraperitoneal Chemotherapy to Treat Peritoneal Carcinomatosis

NCT00052962

COMPLETED Phase 2

Oblimersen Sodium and Rituximab in Treating Patients With Recurrent B-cell Non-Hodgkin Lymphoma

NCT00054639

COMPLETED Phase 2

Vaccine Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma

NCT00054535

COMPLETED Phase 1

Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction

NCT00054483

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What is open in the National Cancer Institute (NCI) pipeline

326 recruiting of 3,257 indexed (10% open); 2,051 completed (63%).

Phase mix: 193 late (III/IV) vs 2,628 early (I/II) (early-phase heavy).

Top condition: Advanced Malignant Solid Neoplasm (67 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.