Melinta Therapeutics

31 total trials 29 completed

Melinta Therapeutics sponsors 31 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 29 completed. 10 of these trials are in Phase 3-4 (later-stage) and 20 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cellulitis, with 2 trials.

Trial Pipeline

31 total, page 1 of 1

COMPLETED Phase 2

Study to Evaluate the Safety of Intravenous Oritavancin for the Treatment of Children With Skin Infections

NCT05599295

COMPLETED Phase 1

Relative Exposure and Safety Study of Kimyrsa in ABSSSI Patients

NCT03873987

COMPLETED Phase 1

Evaluate Safety and Pharmacokinetic To Assess Bronchopulmonary Disposition of Intravenous Delafloxacin in Healthy Adults

NCT03534622

COMPLETED

A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Orbactiv® (Oritavancin) for Infections Caused by Gram Positive Bacteria in a Real World Setting

NCT03159403

COMPLETED Phase 3

Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia

NCT02679573

TERMINATED Phase 2

Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia

NCT02605122

COMPLETED Phase 2

Safety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis

NCT02510599

COMPLETED Phase 1

Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects

NCT02505997

COMPLETED Phase 1

Multiple Oritavancin Doses on Safety, Tolerability, and Pharmacokinetics in Healthy Subjects

NCT02470702

COMPLETED Phase 1

Drug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects

NCT02340988

COMPLETED Phase 1

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

NCT02268279

COMPLETED Phase 3

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP

NCT02166476

COMPLETED Phase 1

Pharmacokinetics of Delafloxacin in Subjects With and Without Hepatic Impairment

NCT02245243

COMPLETED Phase 3

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

NCT02210325

COMPLETED Phase 3

Delafloxacin vs Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections

NCT01984684

COMPLETED Phase 1

Open Label, Dose-finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Participants With Suspected or Confirmed Bacterial Infections

NCT02134301

TERMINATED Phase 3

Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea

NCT02015637

COMPLETED Phase 1

Pharmacokinetics and Safety of Solithromycin Capsules in Adolescents

NCT01966055

COMPLETED Phase 3

Efficacy and Safety Study of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia

NCT01968733

COMPLETED Phase 3

Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections

NCT01811732

COMPLETED Phase 1

Open Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunteers

NCT01784536

COMPLETED Phase 1

A Study to Assess the Cardiac Safety of Oritavancin in Healthy Participants

NCT01762839

COMPLETED Phase 3

Efficacy and Safety Study of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia

NCT01756339

COMPLETED Phase 2

Safety and Efficacy Study of Single-Dose Oral CEM-101 in Patients With Uncomplicated Urogenital Gonorrhea

NCT01591447

COMPLETED Phase 2

A Study to Assess Objective Endpoint Measurements of Response in Bacterial Skin Infections

NCT01283581

COMPLETED Phase 3

Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection

NCT01252732

COMPLETED Phase 3

Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I)

NCT01252719

COMPLETED Phase 2

Efficacy and Safety Study of Oral CEM-101 Compared to Oral Levofloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia

NCT01168713

COMPLETED Phase 2

Safety and Efficacy Study of a Fluoroquinolone to Treat Complicated Skin Infections

NCT00719810

COMPLETED Phase 2

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

NCT00646958

COMPLETED Phase 2

Safety and Efficacy Study of Oxazolidinone to Treat Pneumonia

NCT00640926

What the Pipeline for Melinta Therapeutics Shows

According to the ClinicalTrials.gov registry, Melinta Therapeutics is linked to 31 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 29 are already marked complete, representing roughly 94% of the total.

The phase mix for Melinta Therapeutics reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 20 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Melinta Therapeutics is Cellulitis with 2 linked trials, and 8 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.