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NCT02210325 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

A Phase 3 study of Uncomplicated Urogenital Gonorrhea, sponsored by Melinta Therapeutics.

Completed
Registry status
Phase 3
Development phase
264
Enrollment target
5
Study locations

NCT02210325 is a Phase 3 study of Uncomplicated Urogenital Gonorrhea that has completed, run by Melinta Therapeutics. The registered enrollment target is 264 participants. The trial reports 5 study locations across 4 states.

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The verdict

NCT02210325, a Phase 3 study of Uncomplicated Urogenital Gonorrhea, has completed, sponsored by Melinta Therapeutics.

COMPLETED
Registry status
Phase 3
Development phase
264 participants
Enrollment target
5
Study locations

Study Summary

This study will compare a single dose of oral solithromycin to the standard of care (intramuscular ceftriaxone plus oral azithromycin) in the treatment of patients with urogenital gonorrhea. A completed open-label Phase 2 study with single doses of solithromycin resulted in 100% microbiological eradication in male and female patients with uncomplicated urogenital gonorrhea.

Interventions

  • DRUG azithromycin
  • DRUG ceftriaxone
  • DRUG solithromycin

Study Locations (5)

Ohio

  • - Cleveland
  • - Toledo

Maryland

  • - Baltimore

New South Wales

  • - Sydney

Victoria

  • - Melbourne

Trial Details

FieldValue
Enrollment Target 264 participants
Start Date 2014-08
Est. Completion 2017-02-22
Phase Phase 3

Sponsor

Melinta Therapeutics

31 total trials

What the Registry Record Tells You About NCT02210325

The ClinicalTrials.gov registry entry for NCT02210325 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 264 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Melinta Therapeutics, which has 31 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Uncomplicated Urogenital Gonorrhea appearing as the primary indexed condition, and to 3 interventions - of which azithromycin is the first listed.

NCT02210325 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Ohio, Maryland, New South Wales.

Frequently Asked Questions

What is clinical trial NCT02210325 about?

NCT02210325 is a clinical study titled "Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea". This study will compare a single dose of oral solithromycin to the standard of care (intramuscular ceftriaxone plus oral azithromycin) in the treatment of patients with urogenital gonorrhea. A completed open-label Phase 2 study with single doses of solithromycin resulted in 100% microbiological erad...

What is the current status of trial NCT02210325?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 264 participants. The study started on 2014-08. Estimated completion is 2017-02-22.

What conditions does trial NCT02210325 study?

This clinical trial studies the following conditions: Uncomplicated Urogenital Gonorrhea.

What interventions are being tested in trial NCT02210325?

The interventions under investigation include: azithromycin (DRUG), ceftriaxone (DRUG), solithromycin (DRUG).

Who is sponsoring clinical trial NCT02210325?

This trial is sponsored by Melinta Therapeutics, which has 31 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02210325 being conducted?

This trial has 5 study locations across Maryland, Ohio, New South Wales, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.