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NCT00646958 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections
A Phase 2 study, sponsored by Melinta Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 150
- Enrollment target
NCT00646958: Completed Phase 2 study, sponsored by Melinta Therapeutics.
NCT00646958 is a Phase 2 study that has completed, run by Melinta Therapeutics. The registered enrollment target is 150 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00646958, a Phase 2 study, has completed, sponsored by Melinta Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 150 participants
- Enrollment target
Study Summary
The purpose of this study is to assess the efficacy, safety and tolerability of RX-1741, an oxazolidinone, versus linezolid, another oxazolidinone, in the treatment of uncomplicated skin and skin structure infections
Primary Outcome
To qualify as a Cure, participants were required to fulfill the following criteria: all systemic signs and symptoms of uSSSI present at screening were improved or resolved; no further antibiotic therapy was necessary for treatment of uSSSI; and there was no worsening or appearance of new signs and symptoms of uSSSI.
Interventions
- DRUG Linezolid
- DRUG Radezolid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2007-12 |
| Est. Completion | 2008-04 |
| Phase | Phase 2 |
What the finished NCT00646958 record still lists
NCT00646958 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher).
The record links to 0 conditions, and to 2 interventions - of which Linezolid is the first listed.
NCT00646958 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00646958 about?
NCT00646958 is a clinical study titled "Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections". The purpose of this study is to assess the efficacy, safety and tolerability of RX-1741, an oxazolidinone, versus linezolid, another oxazolidinone, in the treatment of uncomplicated skin and skin structure infections
What is the current status of trial NCT00646958?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2007-12. Estimated completion is 2008-04.
What interventions are being tested in trial NCT00646958?
The interventions under investigation include: Linezolid (DRUG), Radezolid (DRUG).
Who is sponsoring clinical trial NCT00646958?
This trial is sponsored by Melinta Therapeutics, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00646958's enrollment target sits among peer trials
150 455th of 2000 higher than 1,510 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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