Marinus Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Marinus Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#772 of 15,742 sponsors by registered trial count).

19 total trials none currently recruiting 16 completed early-phase tilt top decile by trial count

Marinus Pharmaceuticals: 19 sponsored US clinical trials, none currently recruiting.

Marinus Pharmaceuticals sponsors 19 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 16 completed. 6 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Drug Resistant Partial Onset Seizure, with 1 trials.

Top-decile sponsor footprint

Marinus Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#772 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 50/100

16 of 19 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

19 total, page 1 of 1

TERMINATED Phase 3

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

NCT05604170

COMPLETED Phase 3

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

NCT05323734

COMPLETED Phase 3

Randomized Therapy In Status Epilepticus

NCT04391569

COMPLETED Phase 2

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)

NCT04285346

COMPLETED Phase 2

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

NCT03865732

COMPLETED Phase 3

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

NCT03572933

COMPLETED Phase 2

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

NCT03350035

COMPLETED Phase 2

A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression

NCT03460756

COMPLETED Phase 2

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

NCT03228394

COMPLETED Phase 2

Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies

NCT02358538

TERMINATED Phase 3

A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset Seizures

NCT02519439

COMPLETED Phase 3

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

NCT01963208

COMPLETED Phase 2

Ganaxolone Treatment in Children With Fragile X Syndrome

NCT01725152

COMPLETED Phase 2

Ganaxolone in Posttraumatic Stress Disorder (PTSD)

NCT01339689

COMPLETED Phase 2

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601

NCT01002820

COMPLETED Phase 2

Open-label Extension to Protocol 1042-0600

NCT00512317

COMPLETED Phase 2

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

NCT00465517

COMPLETED Phase 2

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

NCT00441896

TERMINATED Phase 2

Open-label Extension to Protocol 1042-0500

NCT00442104

Phase Distribution

PhaseTrial count
Phase 2 13
Phase 3 6

How the Marinus Pharmaceuticals early-phase archive is shaped

19 indexed studies, none listed as recruiting (0% open); 16 completed (84%).

Phase mix: 6 late (III/IV) vs 13 early (I/II) (early-phase heavy).

Top condition: Drug Resistant Partial Onset Seizure (1 trial), 1 other listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Marinus Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 19 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Marinus Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05101520 0%5%10%15% Total trials Recruiting share Marinus PharmaceuticalsAlmirall, S.A.Bastyr UniversityChurch & Dwight CompanyCordis US10xBio22nd Century Group23andMe3-C Institute for Social Development
Marinus Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Marinus Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 19 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Marinus Pharmaceuticals page

19 registered trials is a research-attention snapshot, not an endorsement of Marinus Pharmaceuticals or any single study.

  • None of Marinus Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Drug Resistant Partial Onset Seizure is the condition Marinus Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Drug Resistant Partial Onset Seizure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Marinus Pharmaceuticals pipeline card: 19 registered trials from official public datasets.Report a data error.