Marinus Pharmaceuticals

19 total trials 16 completed

Marinus Pharmaceuticals sponsors 19 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 16 completed. 6 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Drug Resistant Partial Onset Seizure, with 1 trials.

Trial Pipeline

19 total, page 1 of 1

TERMINATED Phase 3

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

NCT05604170

COMPLETED Phase 3

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

NCT05323734

COMPLETED Phase 3

Randomized Therapy In Status Epilepticus

NCT04391569

COMPLETED Phase 2

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)

NCT04285346

COMPLETED Phase 2

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

NCT03865732

COMPLETED Phase 3

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

NCT03572933

COMPLETED Phase 2

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

NCT03350035

COMPLETED Phase 2

A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression

NCT03460756

COMPLETED Phase 2

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

NCT03228394

COMPLETED Phase 2

Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies

NCT02358538

TERMINATED Phase 3

A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset Seizures

NCT02519439

COMPLETED Phase 3

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

NCT01963208

COMPLETED Phase 2

Ganaxolone Treatment in Children With Fragile X Syndrome

NCT01725152

COMPLETED Phase 2

Ganaxolone in Posttraumatic Stress Disorder (PTSD)

NCT01339689

COMPLETED Phase 2

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601

NCT01002820

COMPLETED Phase 2

Open-label Extension to Protocol 1042-0600

NCT00512317

COMPLETED Phase 2

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

NCT00465517

COMPLETED Phase 2

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

NCT00441896

TERMINATED Phase 2

Open-label Extension to Protocol 1042-0500

NCT00442104

Phase Distribution

PhaseTrial count
Phase 2 13
Phase 3 6

What the Pipeline for Marinus Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Marinus Pharmaceuticals is linked to 19 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 16 are already marked complete, representing roughly 84% of the total.

The phase mix for Marinus Pharmaceuticals reports 6 late-stage studies (Phase 3 and Phase 4 combined) and 13 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Marinus Pharmaceuticals is Drug Resistant Partial Onset Seizure with 1 linked trial, and 1 other condition area appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.