Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00442104 · ClinicalTrials.gov registry record · Phase 2
Open-label Extension to Protocol 1042-0500
A Phase 2 study, sponsored by Marinus Pharmaceuticals.
- Terminated
- Registry status
- Phase 2
- Development phase
- 54
- Enrollment target
NCT00442104: Clinical Trial Phase 2 study, sponsored by Marinus Pharmaceuticals.
NCT00442104 is a Phase 2 study that was terminated before completion, run by Marinus Pharmaceuticals. The registered enrollment target is 54 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00442104, a Phase 2 study, was terminated before completion, sponsored by Marinus Pharmaceuticals.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 54 participants
- Enrollment target
Study Summary
To allow open-label extension to patients who have completed Protocol 1042-0500
Primary Outcome
Clinical spasms were determined by video-electroencephalography (VEEG). The number of participants with spasm-free duration have been presented.
Interventions
- DRUG Ganaxolone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2007-01 |
| Est. Completion | 2009-03 |
| Phase | Phase 2 |
Why NCT00442104 stopped before completion
NCT00442104 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower).
The record links to 0 conditions, and to 1 intervention - of which Ganaxolone is the first listed.
NCT00442104 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00442104 about?
NCT00442104 is a clinical study titled "Open-label Extension to Protocol 1042-0500". To allow open-label extension to patients who have completed Protocol 1042-0500
What is the current status of trial NCT00442104?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 54 participants. The study started on 2007-01. Estimated completion is 2009-03.
What interventions are being tested in trial NCT00442104?
The interventions under investigation include: Ganaxolone (DRUG).
Who is sponsoring clinical trial NCT00442104?
This trial is sponsored by Marinus Pharmaceuticals, which has 19 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00442104's enrollment target sits among peer trials
54 1160th of 2000 higher than 830 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01269853 · 54 participants · Phase 1
Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA
- NCT02390752 · 54 participants · Phase 1
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
- NCT02991248 · 54 participants · NA
Improve Dynamic Lateral Balance of Humans With SCI
- NCT02993900 · 54 participants · NA
Image-Guided Gynecologic Brachytherapy
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia