Ligand Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Ligand Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count).

15 total trials none currently recruiting 15 completed early-phase tilt top decile by trial count

Ligand Pharmaceuticals: 15 sponsored US clinical trials, none currently recruiting.

Ligand Pharmaceuticals sponsors 15 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 15 completed. 2 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sarcoma, Kaposi, with 1 trials.

Top-decile sponsor footprint

Ligand Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

15 of 15 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

15 total, page 1 of 1

COMPLETED Phase 2

A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus

NCT02851849

COMPLETED Phase 1

A Comparison Study of the Bioavailability of a Capsule Formulation of LGD-6972 to an Oral Solution Formulation

NCT02672839

COMPLETED Phase 1

Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus

NCT02250222

COMPLETED Phase 1

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

NCT01919684

COMPLETED Phase 2

A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension

NCT00635232

COMPLETED Phase 2

The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome

NCT00626418

COMPLETED Phase 2

The Effects of Aplindore on the Treatment of Signs and Symptoms of Parkinson's Disease

NCT00623324

COMPLETED Phase 2

A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension

NCT00522925

COMPLETED Phase 2

Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus

NCT00458016

COMPLETED Phase 1

Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma

NCT00073736

COMPLETED Phase 3

Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss

NCT00163137

COMPLETED Phase 3

Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)

NCT00141323

COMPLETED Phase 2

Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma

NCT00006345

COMPLETED Phase 2

Bexarotene in Treating Patients With Metastatic Breast Cancer

NCT00003752

COMPLETED Phase 2

A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma

NCT00002212

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9
Phase 3 2

How the Ligand Pharmaceuticals early-phase archive is shaped

15 indexed studies, none listed as recruiting (0% open); 15 completed (100%).

Phase mix: 2 late (III/IV) vs 13 early (I/II) (early-phase heavy).

Top condition: Sarcoma, Kaposi (1 trial), 2 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Ligand Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 15 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05101520 0%10%20%30%40% Total trials Recruiting share Ligand PharmaceuticalsAllakosArbor Research Collaborative for HealthArena PharmaceuticalsArrowhead Pharmaceuticals10xBio22nd Century Group23andMe3-C Institute for Social Development
Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 15 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Ligand Pharmaceuticals page

15 registered trials is a research-attention snapshot, not an endorsement of Ligand Pharmaceuticals or any single study.

  • None of Ligand Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Sarcoma, Kaposi is the condition Ligand Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sarcoma, Kaposi trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Ligand Pharmaceuticals pipeline card: 15 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.