Ligand Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Ligand Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count).

15 total trials none currently recruiting 15 completed early-phase tilt top decile by trial count

Ligand Pharmaceuticals: 15 sponsored US clinical trials, none currently recruiting.

Ligand Pharmaceuticals sponsors 15 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 15 completed. 2 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sarcoma, Kaposi, with 1 trials.

Top-decile sponsor footprint

Ligand Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

15 of 15 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

15 total, page 1 of 1

COMPLETED Phase 2

A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus

NCT02851849

COMPLETED Phase 1

A Comparison Study of the Bioavailability of a Capsule Formulation of LGD-6972 to an Oral Solution Formulation

NCT02672839

COMPLETED Phase 1

Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus

NCT02250222

COMPLETED Phase 1

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

NCT01919684

COMPLETED Phase 2

A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension

NCT00635232

COMPLETED Phase 2

The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome

NCT00626418

COMPLETED Phase 2

The Effects of Aplindore on the Treatment of Signs and Symptoms of Parkinson's Disease

NCT00623324

COMPLETED Phase 2

A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension

NCT00522925

COMPLETED Phase 2

Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus

NCT00458016

COMPLETED Phase 1

Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma

NCT00073736

COMPLETED Phase 3

Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss

NCT00163137

COMPLETED Phase 3

Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)

NCT00141323

COMPLETED Phase 2

Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma

NCT00006345

COMPLETED Phase 2

Bexarotene in Treating Patients With Metastatic Breast Cancer

NCT00003752

COMPLETED Phase 2

A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma

NCT00002212

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9
Phase 3 2

How the Ligand Pharmaceuticals early-phase archive is shaped

15 indexed studies, none listed as recruiting (0% open); 15 completed (100%).

Phase mix: 2 late (III/IV) vs 13 early (I/II) (early-phase heavy).

Top condition: Sarcoma, Kaposi (1 trial), 2 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Ligand Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 15 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05101520 0%10%20%30%40% Total trials Recruiting share Ligand PharmaceuticalsAllakosArbor Research Collaborative for HealthArena PharmaceuticalsArrowhead Pharmaceuticals10xBio22nd Century Group23andMe3-C Institute for Social Development
Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Ligand Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 15 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Ligand Pharmaceuticals page

15 registered trials is a research-attention snapshot, not an endorsement of Ligand Pharmaceuticals or any single study.

  • None of Ligand Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Sarcoma, Kaposi is the condition Ligand Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sarcoma, Kaposi trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Ligand Pharmaceuticals pipeline card: 15 registered trials from official public datasets.Report a data error.