Krystal Biotech
Krystal Biotech sponsors 13 registered US clinical trials on ClinicalTrials.gov, 8 of them currently recruiting, and 3 completed. 3 of these trials are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Dystrophic Epidermolysis Bullosa, with 3 trials.
Trial Pipeline
13 total, page 1 of 1
A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis
NCT06999733
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
NCT07016750
A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)
NCT06563414
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
NCT06228326
A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency
NCT06049082
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT05970497
A Study Assessing KB407 for the Treatment of Cystic Fibrosis
NCT05504837
Long-Term Follow-up Protocol
NCT04917887
A Study Assessing KB304 for the Treatment of Wrinkles in Women
NCT06724900
A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions
NCT04540900
A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa
NCT04917874
Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB
NCT04491604
A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients
NCT03536143
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 3 | 3 |
Therapeutic Areas
What the Pipeline for Krystal Biotech Shows
According to the ClinicalTrials.gov registry, Krystal Biotech is linked to 13 US clinical trials across every stage of research activity. Of those, 8 studies are currently recruiting, about 62% of the sponsor's indexed portfolio, and 3 are already marked complete, representing roughly 23% of the total.
The phase mix for Krystal Biotech reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 8 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Krystal Biotech is Dystrophic Epidermolysis Bullosa with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.