Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Dystrophic Epidermolysis Bullosa: early-phase trial registry
5 of 8 indexed Dystrophic Epidermolysis Bullosa trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 5 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Dystrophic Epidermolysis Bullosa: 8 US clinical trials tracked, 5 recruiting.
Dystrophic Epidermolysis Bullosa is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Krystal Biotech, running 3 of these trials.
Enrollment posture brief
Registry condition dystrophic-epidermolysis-bullosa
OPEN 5 | RECR 63% | LATE 2 | EARLY 5 | RANK #2176 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Adolescent (63% recruiting · 16 trials)
Dystrophic Epidermolysis Bullosa lists 5 open slots (63% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Dystrophic Epidermolysis Bullosa on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Dystrophic Epidermolysis Bullosa is recruiting above its size-band peers.
5 of 8 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Dystrophic Epidermolysis Bullosa research.
Krystal Biotech accounts for 3 of 8 trials (37.5%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Dystrophic Epidermolysis Bullosa trials plan to enrol fewer than 100 people.
Median target enrolment is 12 among the 8 trials that report a genuine target (sentinel values excluded). 8 of those (100%) plan for fewer than 100 participants.
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Dystrophic Epidermolysis Bullosa research is mostly interventional.
7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Long-Term Follow-up Protocol
Krystal Biotech
NCT04917887
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
Krystal Biotech
NCT07016750
Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa
M. Peter Marinkovich
NCT06834035
MSC EVs in Dystrophic Epidermolysis Bullosa
Aegle Therapeutics
NCT04173650
Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa
Anterogen Co.
NCT05157958
Evaluation of D-Fi for the Treatment of Wounds Due to DEB
Castle Creek Biosciences
NCT06892639
A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients
Krystal Biotech
NCT03536143
To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB)
Castle Creek Pharmaceuticals
NCT03472287
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 1 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Dystrophic Epidermolysis Bullosa records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Dystrophic Epidermolysis Bullosa trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Dystrophic Epidermolysis Bullosa page
8 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Dystrophic Epidermolysis Bullosa trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Krystal Biotech sponsors the most Dystrophic Epidermolysis Bullosa trials on record, review their full trial history before evaluating a specific study. See Krystal Biotech's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dystrophic Epidermolysis Bullosa condition card totals 8 registered trials; most-linked intervention Diacerein 1% Ointment; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.