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NCT06724900 · ClinicalTrials.gov registry record · Phase 1
A Study Assessing KB304 for the Treatment of Wrinkles in Women
A Phase 1 study of Pigmentation and Décolleté Wrinkles, sponsored by Krystal Biotech.
- Active
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT06724900: Active Phase 1 study of Pigmentation and Décolleté Wrinkles, sponsored by Krystal Biotech.
NCT06724900 is a Phase 1 study of Pigmentation and Décolleté Wrinkles that is active but no longer recruiting, run by Krystal Biotech. The registered enrollment target is 19 participants, below the 45-participant average among 4 other Pigmentation trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06724900, a Phase 1 study of Pigmentation and Décolleté Wrinkles, is active but no longer recruiting, sponsored by Krystal Biotech.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area). KB304 is an investigational gene therapy that delivers functional, full-length human collagen (COL3) and elastin (tropoelastin) to the skin through small injections using the Sponsor's genetically engineered Herpes Simplex Virus (HSV-1) vector. The study is a randomized double-blind study and participants will receive either KB304 (active group) or placebo (inactive group).
Primary Outcome
Treatment related adverse events as assessed by CTCAE
Conditions Studied
Interventions
- BIOLOGICAL KB304
- DRUG 0.9% Normal Saline (NS)
Study Locations (1)
California
- Steve Yoelin Medical Associates - Newport Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2024-11-20 |
| Est. Completion | 2025-08 |
| Phase | Phase 1 |
What the registry record for NCT06724900 still lists
NCT06724900 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 45-participant average among 4 other Pigmentation trials with a reported enrollment target (58% lower).
The record links to 3 conditions, with Pigmentation appearing as the primary indexed condition, and to 2 interventions - of which KB304 is the first listed.
NCT06724900 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06724900 about?
NCT06724900 is a clinical study titled "A Study Assessing KB304 for the Treatment of Wrinkles in Women". The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area). KB304 is an investigational gene therapy that delivers functional, full-length human collagen (COL3) and ela...
What is the current status of trial NCT06724900?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2024-11-20. Estimated completion is 2025-08.
What conditions does trial NCT06724900 study?
This clinical trial studies the following conditions: Pigmentation, Décolleté Wrinkles, Wrinkles in Decolletage.
What interventions are being tested in trial NCT06724900?
The interventions under investigation include: KB304 (BIOLOGICAL), 0.9% Normal Saline (NS) (DRUG).
Who is sponsoring clinical trial NCT06724900?
This trial is sponsored by Krystal Biotech, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06724900 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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