Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06724900 · ClinicalTrials.gov registry record · Phase 1
A Study Assessing KB304 for the Treatment of Wrinkles in Women
A Phase 1 study of Pigmentation and Décolleté Wrinkles, sponsored by Krystal Biotech.
- Active
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT06724900 is a Phase 1 study of Pigmentation and Décolleté Wrinkles that is active but no longer recruiting, run by Krystal Biotech. The registered enrollment target is 19 participants, below the 45-participant average among 4 other Pigmentation trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06724900, a Phase 1 study of Pigmentation and Décolleté Wrinkles, is active but no longer recruiting, sponsored by Krystal Biotech.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area). KB304 is an investigational gene therapy that delivers functional, full-length human collagen (COL3) and elastin (tropoelastin) to the skin through small injections using the Sponsor's genetically engineered Herpes Simplex Virus (HSV-1) vector. The study is a randomized double-blind study and participants will receive either KB304 (active group) or placebo (inactive group).
Conditions Studied
Interventions
- BIOLOGICAL KB304
- DRUG 0.9% Normal Saline (NS)
Study Locations (1)
California
- Steve Yoelin Medical Associates - Newport Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2024-11-20 |
| Est. Completion | 2025-08 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06724900
The ClinicalTrials.gov registry entry for NCT06724900 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 45-participant average among 4 other Pigmentation trials with a reported enrollment target (58% lower). The listed sponsor is Krystal Biotech, which has 13 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Pigmentation appearing as the primary indexed condition, and to 2 interventions - of which KB304 is the first listed.
NCT06724900 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06724900 about?
NCT06724900 is a clinical study titled "A Study Assessing KB304 for the Treatment of Wrinkles in Women". The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area). KB304 is an investigational gene therapy that delivers functional, full-length human collagen (COL3) and ela...
What is the current status of trial NCT06724900?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2024-11-20. Estimated completion is 2025-08.
What conditions does trial NCT06724900 study?
This clinical trial studies the following conditions: Pigmentation, Décolleté Wrinkles, Wrinkles in Decolletage.
What interventions are being tested in trial NCT06724900?
The interventions under investigation include: KB304 (BIOLOGICAL), 0.9% Normal Saline (NS) (DRUG).
Who is sponsoring clinical trial NCT06724900?
This trial is sponsored by Krystal Biotech, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06724900 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pigmentation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles
RECRUITING · NA
-
The Effects of Almond on Facial Skin Collagen and Wrinkles
RECRUITING · NA
-
Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study
COMPLETED · NA
-
Evaluation of the Efficacy and Safety of PiQo4 System for the Treatment of Pigmented Lesions
COMPLETED · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.